Comparison of Dietary Modifications with and without Aerobic Exercises in Improving the Cholesterol Lipid Profile for Treatment of Hyperlipidemia-Naïve Patients

Comparison of Dietary Modifications

Authors

  • Qurrat-ul-ain Nazar Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Faizan Hamid Riphah International University Lahore, Pakistan
  • Ahsan Javed Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Zubair bin Ilyas Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Sameera Nawazish Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Muhammad Irfan Aleem Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Usman Mubashir Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan
  • Hafiz Rana Muhammad Arsalan Department of Physiotherapy University of South Asia Cantt Campus, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i11.1090

Keywords:

Aerobic Exercise Training, Dietary Restriction, Hyperlipidemia-Naïve, Cardiovascular disease

Abstract

Hyperlipidemia describes a condition in which an abnormal mass metabolism brought on by a variety of factors raises blood cholesterol levels. According to epidemiological research, there is a strong link between the lipoprotein profile and cardiovascular morbidity and mortality, and those who are physically active have a 30 to 50% lower chance of developing cardiovascular disease. Objective: To compare the effect of dietary modifications with and without aerobic exercises in improving the cholesterol lipid profile for treatment of Hyperlipidemia-Naïve patients. Methods: The random sampling technique with random allocation done through the Lottery method. Lipid Profile Test was used as measuring tool. Whole procedure went through three steps: Pre-Labs Testing, 10 - Weeks Intervention Sessions, and Post-Labs Testing. 24 patients were randomly divided into two groups i.e., Experimental Group and the Control Group, each with 12 patients. After the intervention plan, results were analyzed, organized and interpreted. Results: Normally distributed variables were HDL-C, Cholesterol and VLDL-C with p > 0.05. Whereas, Triglycerides and LDL-C were not distributed normally i.e., p < 0.05.  After the exercise program accomplished as instructed, a statistically significant decrease was observed in the values of Cholesterol, HDL-C, and VLDL-C with the value of p <0.05 for experimental group. However, values of Triglycerides and LDL-C were significantly decreased for the control group. Conclusions: The inclusion of aerobic exercises along with dietary changes substantially enhanced the patient's lipid profile, and exercise program's scope was adequate to produce meaningful changes in the body lipid composition of the study volunteers.

References

Zhao S, Zhong J, Sun C, Zhang J. Effects of aerobic exercise on TC, HDL-C, LDL-C and TG in patients with hyperlipidemia: A protocol of systematic review and meta-analysis. Medicine. 2021 Mar; 100(10): 25103. doi: 10.1097/MD.0000000000025103. DOI: https://doi.org/10.1097/MD.0000000000025103

Varady KA and Jones PJ. Combination diet and exercise interventions for the treatment of dyslipidemia: An effective preliminary strategy to lower cholesterol levels? The Journal of Nutrition. 2005 Aug; 135(8): 1829-35. doi: 10.1093/jn/135.8.1829. DOI: https://doi.org/10.1093/jn/135.8.1829

Mann S, Beedie C, Jimenez A. Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Medicine. 2014 Feb; 44: 211-21. doi:10.1007/s40279-013-0110-5. DOI: https://doi.org/10.1007/s40279-013-0110-5

Yoshida H, Ishikawa T, Suto M, Kurosawa H, Hirowatari Y, Ito K, et al., Effects of supervised aerobic exercise training on serum adiponectin and parameters of lipid and glucose metabolism in subjects with moderate dyslipidemia. Journal of Atherosclerosis and Thrombosis. 2010; 17(11): 1160-6. doi: 10.5551/jat.4358. DOI: https://doi.org/10.5551/jat.4358

Costa RR, Buttelli AC, Coconcelli L, Pereira LF, Vieira AF, Fagundes AD, et al., Water-based aerobic and resistance training as a treatment to improve the lipid profile of women with dyslipidemia: a randomized controlled trial. Journal of Physical Activity and Health. 2019 May; 16(5): 348-54. doi: 10.1123/jpah.2018-0602. DOI: https://doi.org/10.1123/jpah.2018-0602

Yang L, Li Z, Song Y, Liu Y, Zhao H, Liu Y, et al., Study on urine metabolic profiling and pathogenesis of hyperlipidemia. Clinica Chimica Acta. 2019 Aug; 495: 365-73. doi: 10.1016/j.cca.2019.05.001. DOI: https://doi.org/10.1016/j.cca.2019.05.001

Su X, Peng H, Chen X, Wu X, Wang B. Hyperlipidemia and hypothyroidism. Clinica Chimica Acta. 2022 Feb; 527: 61-70. doi: 10.1016/j.cca.2022.01.006. DOI: https://doi.org/10.1016/j.cca.2022.01.006

El-Tantawy WH and Temraz A. Natural products for controlling hyperlipidemia. Archives of Physiology and Biochemistry. 2019 Mar; 125(2): 128-35. doi: 10.1080/13813455.2018.1441315. DOI: https://doi.org/10.1080/13813455.2018.1441315

Mosteoru S, Gaiţă L, Gaiţă D. Sport as Medicine for Dyslipidemia (and Other Risk Factors). Current Atherosclerosis Reports. 2023 Sep; 25(9): 613-7. doi: 10.1007/s11883-023-01133-y. DOI: https://doi.org/10.1007/s11883-023-01133-y

Hazar K, Polat M, Hazar S, Akyüz T. Effects of Eight-Week Moderate Intensity Aerobic Exercises on Dyslipidemia and Body Composition for Overweight and Obese First-Degree Females. Pakistan Journal of Medical & Health Sciences. 2021; 15(4): 1592-608.

Ngayimbesha A, Bizimana JB, Gakima MS. Effect of eight weeks of exercise training on lipid profile and insulin sensitivity in obese person. International Jornals of Sports Exercise and Medicine. 2019; 5(2): 119-25. doi: 10.23937/2469-5718/1510119. DOI: https://doi.org/10.23937/2469-5718/1510119

Doewes RI, Gharibian G, Zaman BA, Akhavan-Sigari R. An updated systematic review on the effects of aerobic exercise on human blood lipid profile. Current Problems in Cardiology. 2023 May; 48(5): 101108. doi: 10.1016/j.cpcardiol.2022.101108. DOI: https://doi.org/10.1016/j.cpcardiol.2022.101108

Kodama S, Tanaka S, Saito K, Shu M, Sone Y, Onitake F, et al., Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Archives of Internal Medicine. 2007 May; 167(10): 999-1008. doi: 10.1001/archinte.167.10.999. DOI: https://doi.org/10.1001/archinte.167.10.999

Tay J, Zajac IT, Thompson CH, Luscombe-Marsh ND, Danthiir V, Noakes M, et al., A randomised-controlled trial of the effects of very low-carbohydrate and high-carbohydrate diets on cognitive performance in patients with type 2 diabetes. British Journal of Nutrition. 2016 Nov; 116(10): 1745-53. doi: 10.1017/S0007114516004001. DOI: https://doi.org/10.1017/S0007114516004001

Iughetti L, Bruzzi P, Predieri B. Evaluation and management of hyperlipidemia in children and adolescents. Current opinion in pediatrics. 2010 Aug; 22(4): 485-93. doi: 10.1097/MOP.0b013e32833ab869. DOI: https://doi.org/10.1097/MOP.0b013e32833ab869

Luo Q, Jin P, Li H, Cui K, Jiang T. Effects of integrated health education combined with life intervention on patients with coronary atherosclerotic heart disease complicated with hyperlipidemia. American Journal of Health Behavior. 2021 Sep; 45(5): 843-8. doi: 10.5993/AJHB.45.5.4. DOI: https://doi.org/10.5993/AJHB.45.5.4

Butt NF, Rathore R, Latif H. Effect of atorvastatin on hematological parameters in patients with dyslipidemias. Hypertension. 2018 Jul; 12(3): 1287-90 .

Evans EM, Saunders MJ, Spano MA, Arngrimsson SA, Lewis RD, Cureton KJ. Body-composition changes with diet and exercise in obese women: a comparison of estimates from clinical methods and a 4-component model. The American Journal of Clinical Nutrition. 1999 Jul; 70(1): 5-12. doi: 10.1093/ajcn/70.1.5. DOI: https://doi.org/10.1093/ajcn/70.1.5

Abdelbasset WK, Nambi G, Alsubaie SF, Elsayed SH, Eid MM, Soliman GS, et al., A Low-Fat Diet Combined with Moderate-Intensity Aerobic Exercise is More Effective than a Low-Fat Diet or Aerobic Exercise Alone on Dyslipidemia and Depression Status in Obese Patients: A Randomized Controlled Trial. Endocrine, Metabolic & Immune Disorders-Drug Targets. 2021 Dec; 21(12): 2289-95. doi: 10.2174/1871530321666210406161226. DOI: https://doi.org/10.2174/1871530321666210406161226

Stefanick ML, Mackey S, Sheehan M, Ellsworth N, Haskell WL, Wood PD. Effects of diet and exercise in men and postmenopausal women with low levels of HDL cholesterol and high levels of LDL cholesterol. New England Journal of Medicine. 1998 Jul; 339(1): 12-20. doi: 10.1056/NEJM199807023390103. DOI: https://doi.org/10.1056/NEJM199807023390103

Downloads

Published

2023-11-30
CITATION
DOI: 10.54393/pjhs.v4i11.1090
Published: 2023-11-30

How to Cite

Nazar, Q.- ul- ain, Hamid, F., Javed, A., Ilyas, Z. bin, Nawazish, S., Aleem, M. I., Mubashir, U., & Muhammad Arsalan, H. R. (2023). Comparison of Dietary Modifications with and without Aerobic Exercises in Improving the Cholesterol Lipid Profile for Treatment of Hyperlipidemia-Naïve Patients: Comparison of Dietary Modifications. Pakistan Journal of Health Sciences, 4(11), 97–103. https://doi.org/10.54393/pjhs.v4i11.1090

Issue

Section

Original Article

Plaudit