Prevalence and Patterns of Electrolyte Imbalance in Children Diagnosed with Acute Severe Malnutrition at a Nutritional Stabilization Center

Electrolyte Imbalance in Severe Acute Malnutrition

Authors

  • . Azizullah Department of Pediatrics, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan
  • Saroop Chand Department of Pediatrics, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Mushtaque Ali Shah Department of Pediatrics, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Abdul Hameed Radhan Department of Pediatrics, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Haseeb Nisar Baloch United Medical and Dental College, Karachi, Pakistan
  • . Nazimuddin Department of Pediatrics, Shaheed Mohtarma Benazir Bhutto Medical College, Larkana, Pakistan
  • Muhammad Nadeem Chohan Department of Pediatrics, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i09.2137

Keywords:

Severe Acute Malnutrition, Electrolyte Imbalance, Hypokalemia, Hyponatremia, Hypocalcemia

Abstract

Malnutrition accounts for around 35% of all fatalities in Pakistan among children under five, making it the primary cause of childhood mortality in that country. The most severe type of malnutrition, known as severe acute malnutrition (SAM), was frequently linked to electrolyte abnormalities. The purpose of this study was to ascertain how frequently electrolyte imbalance occurred in children with SAM who were admitted to a tertiary care facility. Objective: To Determine the Prevalence and Patterns of Electrolyte Imbalance in Children Diagnosed with Acute Severe Malnutrition at a Nutritional Stabilization Center”. Methods: A cross-sectional study was carried out in Nawabshah at the Department of Pediatrics, Peoples University of Medical and Health Sciences, from May 16 to August 15, 2024. This study comprised 92 patients with severe acute malnutrition, ranging in age from 2 to 60 months. Non purposive sampling technique was used for data collection. Children with secondary causes of wasting were excluded, including those with congenital heart disease, chronic renal or liver illness, TB, cancer, and hemolytic anaemia. Weight-for-height was calculated using measurements of weight, length, and height. When the weight-for-height ratio fell below the -3 standard deviation (SD), children were diagnosed with SAM. The lab received blood samples that were taken for serum electrolytes. The chi-square test was used for stratification, and descriptive statistics were computed. Results: Participants' average ages ranged from 23.63± 12.71 months. A total of 85 (93.4%) of the 92 SAM patients had an electrolyte imbalance. The prevalence of hypokalemia (70.08%), hypocalcemia (56.52%), hyponatremia (32.60%), and hypomagnesemia (28.26%), respectively. Conclusions: Children with SAM experience dyselectrolytemia both with and without problems. In all cases of SAM, serum electrolyte levels may need to be assessed in order to identify hyponatremia and hypokalemia in the absence of symptoms. This will facilitate the inpatient treatment triage process for patients with asymptomatic hyponatremia and hypokalemia.

References

Elia M. Defining, recognizing, and reporting malnutrition. The International Journal of Lower Extremity Wounds. 2017 Dec; 16(4): 230-7. doi: 10.1177/1534734617733902.

Kalu RE and Etim KD. Factors associated with malnutrition among underfive children in developing countries: A review. Global Journal of Pure and Applied Sciences. 2018 Jun; 24(1): 69-74. doi: 10.4314/gjpas.v24i1.8.

Raza M, Kumar S, Ejaz M, Azim D, Azizullah S, Hussain A. Electrolyte imbalance in children with severe acute malnutrition at a tertiary care hospital in Pakistan: a cross-sectional study. Cureus. 2020 Sep; 12(9). doi: 10.7759/cureus.10541.

Sridhar NL and Owais MJ. A study of serum electrolytes in malnourished children. Asian Journal of Clinical Pediatrics and Neonatology. 2020 Jan; 8: 41-3. doi: 10.47009/ajcpn.2020.8.1.10.

Laghari GS, Radhan AH, Shaikh SA, Khatti NU, Ahmed ZA, Qambrani KB. Electrolyte imbalances in malnourished under-5 children with or without diarrhoea. Pakistan Journal of Medical & Health Sciences. 2021 Oct; 15. doi: 10.53350/pjmhs2115102670.

Seid MA, Adella GA, Kassie GA, Mengstie MA, Dejenie TA, Zemene MA et al. Serum electrolyte imbalance in severely malnourished children at hospitals in North-central Ethiopia. 2023 Jun. doi: 10.21203/rs.3.rs-3008642/v1.

Hoque MA, Alam HS, Sayeed MA, Al Mamun MA, Islam MN. Electrolyte Changes in Malnourished under-5 Children with or without Diarrhoea. Journal of Shaheed Suhrawardy Medical College. 2020 Jan; 12(1): 50-3. doi: 10.3329/jssmc.v12i1.51619.

Chisti MJ, Salam MA, Ashraf H, Faruque AS, Bardhan PK, Shahid AS et al. Prevalence, clinical predictors, and outcome of hypocalcaemia in severely-malnourished under-five children admitted to an urban hospital in Bangladesh: a case-control study. Journal of Health, Population and Nutrition. 2014 Jun; 32(2): 270-275.

Panda S, Barik RR, Bharaj D, Ranjan J. Clinico-Biochemical Profile of Severe Acute Malnutrition with Special Reference to Infection. International Journal of Academic Medicine and Pharmacy. 2023 Nov; 5(6): 382-6. doi: 10.47009/jamp.2023.5.6.80.

Ashok E, Ramesh S, Prakash SR. Biochemical profile of children with severe acute malnutrition. International Journal of Paediatrics and Geriatrics. 2020; 3: 154-6. doi: 10.33545/26643685.2020.v3.i2c.110.

Ali S, Shahzado A, Chandio S, Chandio S, Chandio K, Pathan S, Fazal K. Hypokalemia Among Children Having Acute Malnutrition with Diarrhea: Children Having Acute Malnutrition with Diarrhea. Pakistan Journal of Health Sciences. 2023 Feb: 125-8. doi: 10.54393/pjhs.v4i02.575.

Meena SK, Suman RL, Jain R, Meena P. Study of serum electrolytes with different clinical co-morbidities in complicated severe acute malnutrition children aged 6 months to 5 years. International Journal of Contemporary Pediatrics. 2017 Jul; 4: 1426-9. doi: 10.18203/2349-3291.ijcp20172679.

ur Rehman M, Khalid A, Khan MA, Khan Z, Sohail A, Khan I. Frequency of Hypokalemia in Malnurished Children with Acute Diarrhea. InMedical Forum Monthly 2021 Feb; 32(2).

Khan S, Rubab Z, Ali I, Arshad R, Abbas A, Akhtar E. The Serum Electrolyte Imbalance in Children with Severe Acute Malnutrition. Journal of Islamic International Medical College. 2021 Mar; 16(1): 10-3.

Memon Y, Majeed R, Ghani MH, Shaikh S. Serum electrolytes changes in malnourished children with diarrhoea. Pakistan Journal of Medical Sciences. 2007 Oct; 23(5): 760.

Zulqarnain A, Jaffar Z, Iqbal I. Malnourished Children with Diarrhea: To Assess the Frequency of Serum Electrolytes (NA+, K+ & CA+) Disturbances. The Professional Medical Journal. 2015 May; 22(05): 610-4. doi: 10.29309/TPMJ/2015.22.05.1275.

Dakshayani B, Ravi M, Premalatha R. A study of serum electrolytes in severe acute malnourished children with and without complications. Indian Journal of Child Health. 2018 Feb; 5(2): 120-3. doi: 10.32677/IJCH.2018.v05.i02.012.

Owais MJ and Sridhar NL. A study of serum electrolytes in malnourished children. Asian Journal of Clinical Pediatrics and Neonatology. 2020 Jan; 8: 41-3. doi: 10.47009/ajcpn.2020.8.1.10.

Bilal A, Sadiq MA, Haider N. Frequency of hyponatraemia and hypokalaemia in malnourished children with acute diarrhoea. Journal of Pakistan Medical Association. 2016 Sep; 66(9): 1077-80.

Kumar D, Rao SK, Singh TB. Clinico-biochemical profile of sick children with severe acute malnutrition. Journal of Family Medicine and Primary Care. 2020 May; 9(5): 2269-72. doi: 10.4103/jfmpc.jfmpc_1236_19.

Verma GK, Yadv RK, Chand R, Khan IA, Katiyar SB, Singh M. Prognostic significance of serum biochemistry profile in children with severe acute malnutrition. Cureus. 2022 Nov; 14(11). doi: 10.7759/cureus.31266.

Ahmad MK. Co-morbidities in Severe Acute Malnutrition with Diarrheal Dyselectrolytemia. European Journal of Molecular and Clinical Medicine. 2021 Jan; 8(3): 4565-71.

Naseem HI, Awais M, Mehmood R, Alam S, Nasir U, Riaz M. Status of Serum Electrolytes among Malnourished Children Presenting with Acute Diarrhea to the Emergency Department of a Teaching Hospital. 2021; 7(1): 43-47.

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Published

2024-09-30
CITATION
DOI: 10.54393/pjhs.v5i09.2137
Published: 2024-09-30

How to Cite

Azizullah, ., Chand, S., Shah, M. A., Radhan, A. H., Baloch, H. N., Nazimuddin, ., & Chohan, M. N. (2024). Prevalence and Patterns of Electrolyte Imbalance in Children Diagnosed with Acute Severe Malnutrition at a Nutritional Stabilization Center: Electrolyte Imbalance in Severe Acute Malnutrition. Pakistan Journal of Health Sciences (Lahore), 5(09), 96–100. https://doi.org/10.54393/pjhs.v5i09.2137

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