The Frequency of Carotid Artery Stenosis in Patients with Ischemic Stroke by Using Color Doppler Ultrasound of Carotid Arteries
Carotid Artery Stenosis in Ischemic Stroke Patients
DOI:
https://doi.org/10.54393/pjhs.v3i07.388Keywords:
Dyslipidemia, Hypertension, Ischemic StrokeAbstract
Stroke is among leading life threatening neurological emergency and single most important reason for disability. Objective: To determine the frequency of carotid artery stenosis in patients with ischemic stroke by using color Doppler ultrasound of carotid arteries. Method: This Cross sectional study was carried out at Medical Unit-III, Abbasi Shaheed Hospital, and Karachi for Six months from 1st December 2017 to 31st May 2018. 170 diagnosed patients of ischemic stroke fulfilling the inclusion criteria were enrolled. Brief history and bio data were entered in the Pro forma. Ultrasound carotid Doppler was done for all the patients included in the study. Effect modifiers were controlled through stratification of age, gender, hypertension, diabetes mellitus, dyslipidemia, obesity, smoking status and history of CVA to see their effect on the outcome variable. Post stratification chi square test/fisher exact test was applied while odds were computed by binary logistic regression taking p-value of ≤0.05 as significant. Results: Among 170 patients with ischemic stroke visiting Medical Unit-III, Abbasi Shaheed Hospital, Karachi who were included in this study, the mean age of patients was 53.14 ±7.49 years and duration of disease was 2.72±0.89 years. 84 (49.4%) were male and 86 (50.6%) were female. Amongst patients with ischemic stroke, 90 (52.9%) had carotid artery stenosis and 80 (47.1%) did not have carotid artery stenosis. Conclusion: Our study showed that notable number of patients with ischemic stroke had carotid artery stenosis; furthermore, risk factors like hypertension, dyslipidemia and smoking were firmly associated with carotid artery stenosis
References
Feigin VL, Stark BA, Johnson CO, Roth GA, Bisignano C, Abady GG, et al. . Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet Neurology. 2021 Oct; 20(10): 795–820. doi: 10.1016/S1474-4422(21)00252-0
Mackay J, Mensah GA, Greenlund K. The atlas of heart disease and stroke. World Health Organization. 2004.
Anwar A, Saleem S, Aamir A, Diwan M. Organization of stroke care in Pakistan. International Journal of Stroke. 2020 Jul; 15(5): 565-6. doi: 10.1177/1747493019879663
Hashmi M, Khan M, Wasay M. Growing burden of stroke in Pakistan: a review of progress and limitations. International journal of stroke. 2013 Oct; 8(7): 575-81. doi: 10.1111/j.1747-4949.2012.00827.x
Shahid S, Khattak AL, Bukhari KH, Uddin R, Khan RI. Asymptomatic Carotid Artery Stenosis among Patients with Type II Diabetes Mellitus. Journal of Bahria University Medical and Dental College. 2021 Mar; 11(1): 27-30. doi: 10.51985/AITH5490.
Song P, Fang Z, Wang H, Cai Y, Rahimi K, Zhu Y, et al. Global and regional prevalence, burden, and risk factors for carotid atherosclerosis: a systematic review, meta-analysis, and modelling study. The Lancet Global Health. 2020 May; 8(5): e721-9. doi: 10.1016/S2214-109X(20)30117-0
Ali M, Khan MN, Patel MJ. Pattern and Knowledge of HbA1C Testing among Diabetic Patients at The Indus Hospital (TIH), Karachi. Liaquat National Journal of Primary Care 2022; 4(2): 102-105. doi: 10.37184/lnjpc.2707-3521.4.19
Tan TY, Chang KC, Liou CW, Reynolds PS, Tegeler CH. Lack of Relation Between Severity of Stroke and Severity of Extracranial Internal Carotid Artery Lesions in Taiwanese First‐Ever Ischemic Stroke Patients. Journal of Neuroimaging. 2001 Oct; 11(4): 381-4. doi: 10.1111/j.1552-6569.2001.tb00066.x
Xing L, Li R, Zhang S, Li D, Dong B, Zhou H, et al. High burden of carotid atherosclerosis in rural Northeast China: a population-based study. Frontiers in Neurology. 2021 Feb; 12: 597992. doi: 10.3389/fneur.2021.597992.
Oglat AA, Matjafri MZ, Suardi N, Oqlat MA, Abdelrahman MA, Oqlat AA. A review of medical doppler ultrasonography of blood flow in general and especially in common carotid artery. Journal of medical ultrasound. 2018 Jan; 26(1): 3. doi: 10.4103/JMU.JMU_11_17
Naylor AR, Ricco JB, de Borst GJ, Debus S, de Haro J, Halliday A, et al. Management of atherosclerotic carotid and vertebral disease: 2017 clinical practice guidelines of the European Society for Vascular Surgery (ESVS). European Journal of Vascular and Endovascular Surgery. 2018; 55(1): 142. doi: 10.1016/j.ejvs.2017.06.021
Razzaq AA, Khan BA, Jadoon CK, Baig SM. Carotid Doppler ultrasonography in young stroke patients. Journal of Pakistan Medical Association. 1999; 49(4): 97-99.
Atif MA, Ali H, Mahmood T. Frequency of carotid atherosclerosis in cerebral infarction. Pakistan Journal of Medical Sciences. 2008 Jan; 24(1): 69-73.
Shaikh NA, Bhatty S, Irfan M, Khatri G, Vaswani AS, Jakhrani N. Frequency, characteristics and risk factors of carotid artery stenosis in ischaemic stroke patients at Civil Hospital Karachi. Journal Of Pakistan Medical Association: JPMA. 2010; 60(8): 8-12
Hadi NU, Khan R, Awan KH, Iqba N. Frequency of carotid artery stenosis in ischemic stroke by using carotid doppler ultrasonography in a teaching hospital. Gomal Journal of Medical Sciences. 2009 Dec; 7(2): 82-86.
Afridi A, Afridi Z, Afridi F, Afridi A. Frequency of carotid artery stenosis in ischemic stroke patients. Journal of Medical Sciences. 2017 Sep; 25(3): 340-3.
Khattak MI, Khan F, Fida Z, Zar A. CAROTID ARTERY STENOSIS: IN ISCHEMIC STROKE PATIENTS. The Professional Medical Journal. 2017 Aug 8; 24(08): 1126-1131. doi: 10.17957/TPMJ/17.4064
Liu J, Zhu Y, Wu Y, Liu Y, Teng Z, Hao Y. Association of carotid atherosclerosis and recurrent cerebral infarction in the Chinese population: a meta-analysis. Neuropsychiatric Disease and Treatment. 2017; 13: 527. doi: 10.2147/NDT.S124386
Khedr E, Tony AA, Habeel M, Nasreldein A. Frequency and risk factors of carotid artery disease among ischemic stroke patients in the south Egypt: hospital-based study. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery. 2021 Dec; 57(1): 1-6. doi: 10.1186/s41983-021-00382-5
Hassan KM, Verma A, Prakash S, Chandran V, Kumar S, Banerji A. Prevalence and association of lifestyle factors with extracranial carotid atherosclerosis in non-cardioembolic anterior circulation strokes in adult males less than 50 years: One year cross-sectional study. Annals of Indian Academy of Neurology. 2013 Oct; 16(4): 516. doi: 10.4103/0972-2327.120448
Siddiqi AM, Ali A, Masrur S, Monga MA, Tauqeer A, Rehman KU. Clinical Audit of Patients with CVA in Medical Unit-I, Jinnah Hospital, Lahore. Annals of King Edward Medical University. 2001; 7(2): 79-82
Khan SN, Vohra EA. Risk factors for stroke: A hospital based study. Pakistan Journal of Medical Sciences. 2007 Jan 1; 23(1): 17-22.
Piravej K, Wiwatkul W. Risk factors for stroke in Thai patients. Journal-medical association of Thailand. 2003 Jun ; 86(SUPP/2): S291-8.
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