Factors Influencing Adherence to Anti-Hypertensive Medication Regimens in Diabetic Patients: A Cross-Sectional Analysis at Hayatabad Medical Complex, Peshawar
Factors Influencing Adherence to Anti-Hypertensive Medication
DOI:
https://doi.org/10.54393/pjhs.v4i09.991Keywords:
Adherence, Diabetes, Antihypertensive Drugs, Cross-Sectional AnalysisAbstract
Adherence to anti-hypertensive medication among diabetic patients is of paramount importance. Objective: To delve deeper into the influential factors that dictate this adherence behavior, thereby leading to improved healthcare outcomes. Methods: A structured questionnaire grounded on the Morisky Medication Adherence Scale (MMAS-8) was employed to gather data from a sample of 301 diabetic patients diagnosed with hypertension at Hayatabad Medical Complex, Peshawar. Parameters such as demographic characteristics, duration of diabetes, and patients' adherence to medication were meticulously recorded and analyzed. Statistical tests such as Chi-square and binary logistic regression were used for data analysis. Results: The study results brought forth that demographic factors like age and gender, coupled with patients' perceptions of their medication, significantly influenced their adherence to anti-hypertensive medication. The study discovered that females were 1.3 times more prone to forget to take their medication relative to males. Furthermore, patients aged below 50 were twice as inclined to discontinue medication when they felt their condition improved. Of particular note, those patients who nurtured misconceptions about the effectiveness and necessity of their medication showed a 1.8 times higher propensity of displaying poor medication adherence. Conclusions: The study underscores the importance of implementing individualized interventions aimed at enhancing medication adherence, especially focusing on female patients, younger patients, and those harboring misconceptions about their medication regimen.
References
Campbell-Lendrum D, and Prüss-Ustün A. Climate change, air pollution and noncommunicable diseases. Bulletin of the World Health Organization. 2019 Feb; 97(2): 160. doi: 10.2471/BLT.18.224295. DOI: https://doi.org/10.2471/BLT.18.224295
Talisuna AO, Okiro EA, Yahaya AA, Stephen M, Bonkoungou B, Musa EO, et al. Spatial and temporal distribution of infectious disease epidemics, disasters and other potential public health emergencies in the World Health Organisation Africa region, 2016–2018. Globalization and Health. 2020 Dec; 16: 1-2. doi: 10.1186/s12992-019-0540-4. DOI: https://doi.org/10.1186/s12992-019-0540-4
Wasay M, and Jabbar A. Fight against chronic diseases (high blood pressure, stroke, diabetes and cancer) in Pakistan; Cost-Effective Interventions. Journal of Pakistan Medical Association. 2009 Apr; 59(4): 167-9.
Whiting DR, Guariguata L, Weil C, Shaw J. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Research and Clinical Practice. 2011 Dec; 94(3): 311-21. doi: 10.1016/j.diabres.2011.10.029. DOI: https://doi.org/10.1016/j.diabres.2011.10.029
Roglic G. WHO Global report on diabetes: A summary. International Journal of Noncommunicable Diseases. 2016 Apr; 1(1): 3-8. doi: 10.4103/2468-8827.184853. DOI: https://doi.org/10.4103/2468-8827.184853
Federation ID. IDF Diabetes Atlas. Brussels, Belgium: International Diabetes Federation; 2013.
Ettehad D, Emdin CA, Kiran A, Anderson SG, Callender T, Emberson J, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. The Lancet. 2016 Mar; 387(10022): 957-67. doi: 10.1016/S0140-6736(15)01225-8. DOI: https://doi.org/10.1016/S0140-6736(15)01225-8
Gupta P, Patel P, Štrauch B, Lai FY, Akbarov A, Marešová V, et al. Risk factors for nonadherence to antihypertensive treatment. Hypertension. 2017 Jun; 69(6): 1113-20. doi: 10.1161/HYPERTENSIONAHA.116.08729. DOI: https://doi.org/10.1161/HYPERTENSIONAHA.116.08729
Lemay J, Waheedi M, Al-Sharqawi S, Bayoud T. Medication adherence in chronic illness: do beliefs about medications play a role? Patient preference and adherence. 2018 Sep: 1687-98. doi: 10.2147/PPA.S169236. DOI: https://doi.org/10.2147/PPA.S169236
Xu HY, Yu YJ, Zhang QH, Hu HY, Li M. Tailored interventions to improve medication adherence for cardiovascular diseases. Frontiers in Pharmacology. 2020 Nov; 11: 510339. doi: 10.3389/fphar.2020.510339. DOI: https://doi.org/10.3389/fphar.2020.510339
Kamran A, Ahari SS, Biria M, Malpour A, Heydari H. Determinants of patient’s adherence to hypertension medications: application of health belief model among rural patients. Annals of Medical and Health Sciences Research. 2014; 4(6): 922-7. doi: 10.4103/2141-9248.144914. DOI: https://doi.org/10.4103/2141-9248.144914
Gheshlagh RG, Parizad N, Ghalenoee M, Dalvand S, Baghi V, Najafi F, et al. Psychometric features of the persian version of self-efficacy tool for patients with hypertension. International Cardiovascular Research Journal. 2018; 12(2): 50-6.
Krueger KP, Felkey BG, Berger BA. Improving adherence persistence: A review assessment of interventions description of steps toward a national adherence initiative. Journal of the American Pharmacists Association. 2003 Nov; 43(6): 668-79. doi: 10.1331/154434503322642598. DOI: https://doi.org/10.1331/154434503322642598
Volpe M, Chin D, Paneni F. The challenge of polypharmacy in cardiovascular medicine. Fundamental & Clinical Pharmacology. 2010 Feb; 24(1): 9-17. doi: 10.1111/j.1472-8206.2009.00757.x. DOI: https://doi.org/10.1111/j.1472-8206.2009.00757.x
Jowett NI, and Cabot LB. Patients with cardiac disease: considerations for the dental practitioner. British Dental Journal. 2000 Sep; 189(6): 297-302. doi: 10.1038/sj.bdj.4800750a. DOI: https://doi.org/10.1038/sj.bdj.4800750a
Vermeire E, Hearnshaw H, Van Royen P, Denekens J. Patient adherence to treatment: three decades of research. A comprehensive review. Journal of Clinical Pharmacy and Therapeutics. 2001 Oct; 26(5): 331-42. doi: 10.1046/j.1365-2710.2001.00363.x. DOI: https://doi.org/10.1046/j.1365-2710.2001.00363.x
Osamor PE, and Owumi BE. Factors associated with treatment compliance in hypertension in southwest Nigeria. Journal of Health, Population, and Nutrition. 2011 Dec; 29(6): 619. doi: 10.3329/jhpn.v29i6.9899. DOI: https://doi.org/10.3329/jhpn.v29i6.9899
Vervloet M, Korevaar JC, Leemrijse CJ, Paget J, Zullig LL, van Dijk L. Interventions to improve adherence to cardiovascular medication: what about gender differences? A systematic literature review. Patient Preference and Adherence. 2020 Oct: 2055-70. doi: 10.2147/PPA.S260562. DOI: https://doi.org/10.2147/PPA.S260562
Hameed MA, Tebbit L, Jacques N, Thomas M, Dasgupta I. Non-adherence to antihypertensive medication is very common among resistant hypertensives: results of a directly observed therapy clinic. Journal of Human Hypertension. 2016 Feb; 30(2): 83-9. doi: 10.1038/jhhd.2015.38. DOI: https://doi.org/10.1038/jhh.2015.38
Neutel JM, and Smith DH. Improving patient compliance: a major goal in the management of hypertension. The Journal of Clinical Hypertension. 2003 Mar; 5(2): 127-32. doi: 10.1111/j.1524-6175.2003.00495.x. DOI: https://doi.org/10.1111/j.1524-6175.2003.00495.x
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Pakistan Journal of Health Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments
