Association between COVID-19 Infection Susceptibility and ABO Blood Groups and Rhesus Antigen

COVID-19 Infection Susceptibility and ABO Blood Groups

Authors

  • Muhammad Umer Khan Institute of Molecular Biology and Biotechnology, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Nauman Khokhar Institute of Molecular Biology and Biotechnology, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Muhammad Ahmad Ashraf Institute of Molecular Biology and Biotechnology, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Muhammad Usman Ghani Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan
  • Saima Younas Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan
  • Iram Amin Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan
  • Muhammad Shahid Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan
  • Inam Ullah Intitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan
  • Rakhtasha Munir Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan
  • Sameen Ahmed Centre for Applied Molecular Biology, University of the Punjab, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i10.1031

Keywords:

COVID-19, ABO Blood Groups, HBGAs, SARS-COV-2

Abstract

COVID-19, caused by the SARS-CoV-2 virus, is a highly contagious disease that has been declared a global pandemic by the World Health Organization, leading to widespread impacts. Objective: To investigate the potential relationship between ABO blood groups and susceptibility to the coronavirus. Methods: This study was conducted at The University of Lahore between April and September 2021. Blood groups of 528 SARS-CoV2-positive patients admitted to various hospitals in Punjab was calculated by both forward and reverse blood grouping technique. Data analysis was performed using the SPSS version 25.0. Results: The mean age was found to be 41.5 years, with a range of 16-90 years, among which 63.3% were male (n = 334) and 36.7% (n = 194) were female. The data were categorized according to blood group type. A+ (13.4%), A- (8.5%), B- (8.7%), B+ (22.5%), O+ (19.5%), O- (4.9%), AB+ (11.9%), and AB- (10.4%). A, B, and AB were associated with high susceptibility to COVID-19 infection, i.e., 75.5% (n = 399), and less frequent in the O blood group, 24.5% (n = 129). RH (D) ve+ type blood group was highest at 67.5% (n = 356) in COVID-19 patients as compared to the RH (D) –ve type blood group at 32.5% (n = 172), respectively. Conclusions: Individuals with blood groups A, B, and AB have been observed to be more susceptible to COVID-19 than those with blood group O. Similarly, individuals who are RH positive are considered more vulnerable to coronavirus than those who are RH negative.

 

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Published

2023-10-31
CITATION
DOI: 10.54393/pjhs.v4i10.1031
Published: 2023-10-31

How to Cite

Khan, M. U., Khokhar, N., Ashraf, M. A., Ghani, M. U., Younas, S., Amin, I., Shahid, M., Ullah, I., Munir, R., & Ahmed, S. (2023). Association between COVID-19 Infection Susceptibility and ABO Blood Groups and Rhesus Antigen : COVID-19 Infection Susceptibility and ABO Blood Groups. Pakistan Journal of Health Sciences, 4(10), 46–50. https://doi.org/10.54393/pjhs.v4i10.1031

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