Chemical Composition of Calculi Removed from Urinary Tract

Chemical Composition of Urinary Calculi

Authors

  • Hassan Raza Asghar Avicenna Medical College and Hospital, Lahore, Pakistan
  • Muhammad Zahid Ahmad King Edward Medical University, Lahore, Pakistan
  • Muhammad Asif King Edward Medical University, Lahore, Pakistan
  • Aftab Ahmed Channa Islam Medical College, Sialkot, Pakistan
  • Nauman Ahmad Government Kot Khwaja Saeed Teaching Hospital, Lahore, Pakistan
  • Abdul Basit Niazi Niazi Medical College, Sargodha, Pakistan
  • Shafqat Shahzad University of the Punjab, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i01.1272

Keywords:

Calculi, Urinary Infection, Uric Acid, Ureterolithotomy

Abstract

Urinary stone (calculi) disease is the most prevalent occurrence in the outpatient urology department by far. It is becoming more and more commonplace. Since most of the calculi might recur, understanding chemical composition is crucial. worldwide. Objective: To analyze the different compositions of calculi removed from urinary tract. Methods: A descriptive study was performed in the Department of Urology, Avicenna Medical College and Hospital, Lahore, from July 2016 to October 2022. 300 Patients operated for urinary stone disease were selected as the sample population. All calculi removed from these patients were subjected to stone analysis and then results were prepared. Results: The most common stone type based on chemical composition was calcium oxalate (52%), followed by uric acid stones (25%), mixed stones (17%) and magnesium ammonium phosphate MAP (5%). Other less common types were accountable for only 1%. Conclusions: Calcium oxalate, uric acid and mixed composition stones are most common varieties in the draining area of our hospital setup. 

References

Thongprayoon C, Krambeck AE, Rule AD. Determining the true burden of kidney stone disease. Nature Reviews Nephrology. 2020 Dec; 16(12): 736-46. doi: 10.1038/s41581-020-0320-7. DOI: https://doi.org/10.1038/s41581-020-0320-7

Zeng G, Mai Z, Xia S, Wang Z, Zhang K, Wang L, et al. Prevalence of kidney stones in China: an ultrasonography based cross‐sectional study. BJU International. 2017 Jul; 120(1): 109-16. doi: 10.1111/bju.13828. DOI: https://doi.org/10.1111/bju.13828

Singh S, Gupta S, Mishra T, Banerjee BD, Sharma T. Risk Factors of Incident Kidney Stones in Indian Adults: A Hospital-Based Cross-Sectional Study. Cureus. 2023 Feb; 15(2): e35558. doi: 10.7759/cureus.35558. DOI: https://doi.org/10.7759/cureus.35558

Raja A, Wood F, Joshi HB. The impact of urinary stone disease and their treatment on patients’ quality of life: a qualitative study. Urolithiasis. 2020 Jun; 48: 227-34. doi: 10.1007/s00240-019-01142-0. DOI: https://doi.org/10.1007/s00240-019-01142-0

Li Y, Bayne D, Wiener S, Ahn J, Stoller M, Chi T. Stone formation in patients less than 20 years of age is associated with higher rates of stone recurrence: results from the Registry for Stones of the Kidney and Ureter (ReSKU). Journal of Pediatric Urology. 2020 Jun; 16(3): 373-e1. doi: 10.1016/j.jpurol.2020.03.014. DOI: https://doi.org/10.1016/j.jpurol.2020.03.014

Prezioso D, Strazzullo P, Lotti T, Bianchi G, Borghi L, Caione P, et al. Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group. Archivio Italiano di Urologia Andrologia. 2015; 87(2): 105-20. doi: 10.4081/aiua.2015.2.105. DOI: https://doi.org/10.4081/aiua.2015.2.105

Kasidas GP, Samuell CT, Weir TB. Renal stone analysis: why and how? Annals of Clinical Biochemistry. 2004 Mar; 41(2): 91-7. doi: 10.1258/000456304322879962. DOI: https://doi.org/10.1258/000456304322879962

Magni G, Unwin RJ, Moochhala SH. Renal tubular acidosis (RTA) and kidney stones: Diagnosis and management. Archivos Espanoles de Urologia. 2021 Jan; 74(1): 123-8.

Menon M. Urinary lithiasis: etiology, diagnosis, and medical management. Campbell's urology. 2002; 4: 3227-92.

Prien EL and Prien Jr EL. Composition and structure of urinary stone. The American Journal of Medicine. 1968 Nov; 45(5): 654-72. doi: 10.1016/0002-9343(68)90202-7. DOI: https://doi.org/10.1016/0002-9343(68)90202-7

Dretler SP. Ureteral stone disease: Options for management. Urologic Clinics of North America. 1990 Feb; 17(1): 217-30. doi: 10.1016/S0094-0143(21)00323-2. DOI: https://doi.org/10.1016/S0094-0143(21)00323-2

Riese RJ and Sakhaee K. Uric acid nephrolithiasis: pathogenesis and treatment. The Journal of Urology. 1992 Sep; 148(3): 765-71. doi: 10.1016/S0022-5347(17)36715-0. DOI: https://doi.org/10.1016/S0022-5347(17)36715-0

Wang P, Zhang H, Zhou J, Jin S, Liu C, Yang B, et al. Study of risk factor of urinary calculi according to the association between stone composition with urine component. Scientific reports. 2021 Apr; 11(1): 8723. doi: 10.1038/s41598-021-87733-7 DOI: https://doi.org/10.1038/s41598-021-87733-7

Daudon M, Petay M, Vimont S, Deniset A, Tielens F, Haymann JP, et al. Urinary tract infection inducing stones: Some clinical and chemical data. Comptes Rendus. Chimie. 2022; 25(S1): 315-34. doi: 10.5802/crchim.159 DOI: https://doi.org/10.5802/crchim.159

Kambal A, Wahab EM, Khattab AH. The composition of urinary stones in the Sudan. British Journal of Urology. 1979 Oct; 51(5): 342-4. doi: 10.1111/j.1464-410X.1979.tb02881.x. DOI: https://doi.org/10.1111/j.1464-410X.1979.tb02881.x

Freeman JA and Beeler MF. Laboratory medicine/urinalysis and medical microscopy. 1983.

Singh VK and Rai PK. Kidney stone analysis techniques and the role of major and trace elements on their pathogenesis: a review. Biophysical Reviews. 2014 Dec; 6(3-4): 291-310. doi: 10.1007/s12551-014-0144-4. doi: 10.1007/s12551-014-0144-4. DOI: https://doi.org/10.1007/s12551-014-0144-4

Zafar MH. Prevalence and type of renal stone in Multan region. PJMR-Pakistan Journal of Medical Research. 1992; 31(1): 13-7.

Shahjehan S and Rahman MA. Studies on the etiology of urolithiasis in Karachi. The American Journal of Clinical Nutrition. 1971 Jan; 24(1): 32-7. doi: 10.1093/ajcn/24.1.32. DOI: https://doi.org/10.1093/ajcn/24.1.32

Sial SJ, Juaid Khan J, Khan AAF. Chemical analysis of Renal Calculi from D.G. Khan Professional Medical Journal. 1995 Apr; 2(2): 89-93.

Rizvi SA. Calculous disease--a survey of 400 patients. The Journal of the Pakistan Medical Association. 1975 Oct; 25(10): 268-74.

Rodgers A. The riddle of kidney stone disease: lessons from Africa. Urological research. 2006 Apr; 34: 92-5. doi: 10.1007/s00240-005-0017-1. DOI: https://doi.org/10.1007/s00240-005-0017-1

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Published

2023-12-31
CITATION
DOI: 10.54393/pjhs.v5i01.1272
Published: 2023-12-31

How to Cite

Raza Asghar, H., Ahmad, M. Z., Asif, M., Channa, A. A., Ahmad, N., Niazi, A. B., & Shahzad, S. (2023). Chemical Composition of Calculi Removed from Urinary Tract : Chemical Composition of Urinary Calculi . Pakistan Journal of Health Sciences, 5(01), 96–99. https://doi.org/10.54393/pjhs.v5i01.1272

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