The Impact of Lifestyle Factors on the Development of Kidney Stones: Lifestyle Factors on the Kidney Stones Development

Nisar Ahmad; Ijaz Ur Rehman; Khalid Khan; Mian Latif Javed; Mohammad Faisal; Rida Naz

doi:10.54393/pjhs.v5i11.1911

Authors

Nisar Ahmad Department of Urology, Sahiwal Medical College, Sahiwal Teaching Hospital, Sahiwal, Pakistan
Ijaz Ur Rehman Department of Urology, Gomal Medical College, District Head Quarter Teaching Hospital, Dera Ismail Khan, Pakistan
Khalid Khan Department of Urology, Sahiwal Medical College, Sahiwal Teaching Hospital, Sahiwal, Pakistan
Mian Latif Javed Department of Urology, Sahiwal Medical College, Sahiwal Teaching Hospital, Sahiwal, Pakistan
Mohammad Faisal Department of Community Medicine, Gomal Medical College, Dera Ismail Khan, Pakistan
Rida Naz Regional Blood Centre, Dera Ismail Khan, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i11.1911

Keywords:

Hydration, Kidney Stones, Lifestyle Factors, Physical activity

Abstract

Kidney stones are a common urological condition affecting millions worldwide, and lifestyle factors significantly influence their risk. Objectives: To assess the correlation between the risk of kidney stones and dietary habits, physical activity levels, hydration status, and body mass index in a cohort of 220 participants at Gomal Medical College, Dera Ismail Khan. Methods: A cross-sectional study was executed, with 220 adults stratified into two groups based on presence (n=111) or absence (n=109) of kidney stones. Validated structured questionnaires assessing hydration level, physical activity, body mass index, socioeconomic level, and dietary intake; animal protein, oxalates, and sodium were used to compile data. Chi-square testing and logistic regression allowed one to compute the odds ratios for kidney stone risk. Results: Significant risk factors for kidney stones were shown by high intake of animal protein (OR=3.88, p<0.001), high sodium intake (OR=1.98, p<0.05), and high oxalate intake (OR=1.65, p<0.05). High physical activity and adequate hydration were protective against kidney stones. A greater body mass index (OR=2.33, p<0.01) was linked to a higher risk. Socioeconomic level and stone frequency showed an association; the lower status was linked to a higher prevalence of stones (OR=1.75, p<0.05). Conclusions: It was concluded that the study underlined the strong relationships between particular lifestyle choices and kidney stone development probability. Good preventive measures are keeping an active lifestyle, making sure one is hydrated enough, and controlling their food. These findings highlight the importance of including lifestyle modifications in the clinical management of kidney stones.

References

Alelign T and Petros B. Kidney Stone Disease: An Update on Current Concepts. Advances in Urology. 2018; 2018(1): 3068365. doi: 10.1155/2018/3068365.

Jones P, Karim Sulaiman S, Gamage KN, Tokas T, Jamnadass E, Somani BK. Do Lifestyle Factors Including Smoking, Alcohol, and Exercise Impact Your Risk of Developing Kidney Stone Disease? Outcomes of A Systematic Review. Journal of Endourology. 2021 Jan; 35(1): 1-7. doi: 10.1089/end.2020.0378.

Stamatelou K and Goldfarb DS. Epidemiology of Kidney Stones. In Healthcare. 2023 Feb; 11(3): 424. doi: 10.3390/healthcare11030424.

Ferraro PM, Bargagli M, Trinchieri A, Gambaro G. Risk of Kidney Stones: Influence of Dietary Factors, Dietary Patterns, and Vegetarian–Vegan Diets. Nutrients. 2020 Mar; 12(3): 779. doi: 10.3390/nu12030779.

Khan SR, Pearle MS, Robertson WG, Gambaro G, Canales BK, Doizi S et al. Kidney Stones. Nature Reviews Disease Primers. 2016 Feb; 2(1): 1-23. doi: 10.1038/nrdp.2016.8.

Han H, Segal AM, Seifter JL, Dwyer JT. Nutritional Management of Kidney Stones (Nephrolithiasis). Clinical Nutrition Research. 2015 Jul; 4(3): 137-52. doi: 10.7762/cnr.2015.4.3.137.

Courbebaisse M, Travers S, Bouderlique E, Michon-Colin A, Daudon M, De Mul A et al. Hydration for Adult Patients with Nephrolithiasis: Specificities and Current Recommendations. Nutrients. 2023 Nov; 15(23): 4885. doi: 10.3390/nu15234885.

Gamage KN, Jamnadass E, Sulaiman SK, Pietropaolo A, Aboumarzouk O, Somani BK. The Role of Fluid Intake in the Prevention of Kidney Stone Disease: A Systematic Review Over the Last Two Decades. Turkish Journal of Urology. 2020 Nov; 46(Suppl 1): S92. doi: 10.5152/tud.2020.20155.

Wei Q, Bao Y, Tu X. Water for Preventing Urinary Stones. Cochrane Database of Systematic Reviews. 2020 Fed: 2(2). doi: 10.1002/14651858.CD004292.pub4.

Zyoud SE, Abushamma F, Salameh H, Abushanab AS, Koni A, Abu Taha A et al. Exploring the Nutritional Landscape and Emerging Trends in Kidney Stone Research: Visualization and Bibliometric Analysis. Translational Medicine Communications. 2024 Mar; 9(1): 8. doi: 10.1186/s41231-024-00168-w.

Poore W, Boyd CJ, Singh NP, Wood K, Gower B, Assimos DG. Obesity and Its Impact on Kidney Stone Formation. Reviews in Urology. 2020; 22(1): 17.

Rahman IA, Nusaly IF, Syahrir S, Nusaly H, Mansyur MA. Association Between Metabolic Syndrome Components and the Risk of Developing Nephrolithiasis: A Systematic Review and Bayesian Meta-Analysis. F1000Research. 2021 Feb; 10: 104. doi: 10.12688/f1000research.28346.1.

Arazi H, Mohabbat M, Saidie P, Falahati A, Suzuki K. Effects of Different Types of Exercise On Kidney Diseases. Sports. 2022 Mar; 10(3): 42. doi: 10.3390/sports10030042.

Peerapen P and Thongboonkerd V. Kidney Stone Prevention. Advances in Nutrition. 2023 May; 14(3): 555-69. doi: 10.1016/j.advnut.2023.03.002.

Cheraghian B, Meysam A, Hashemi SJ, Hosseini SA, Malehi AS, Khazaeli D et al. Kidney Stones and Dietary Intake in Adults: A Population-Based Study in Southwest Iran. BioMed Central Public Health. 2024 Apr; 24(1): 955. doi: 10.1186/s12889-024-18393-1.

Zhuo D, Li M, Cheng L, Zhang J, Huang H, Yao Y. A Study of Diet and Lifestyle and the Risk of Urolithiasis in 1,519 Patients in Southern China. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research. 2019 Jun; 25: 4217-4224. doi: 10.12659/MSM.916703.

Sorensen MD, Kahn AJ, Reiner AP, Tseng TY, Shikany JM, Wallace RB et al. Impact of Nutritional Factors on Incident Kidney Stone Formation: A Report from the WHI OS. The Journal of Urology. 2012 May; 187(5): 1645-50. doi: 10.1016/j.juro.2011.12.077.

Sakhaee K, Harvey JA, Padalino PK, Whitson P, Pak CY. The Potential Role of Salt Abuse on the Risk for Kidney Stone Formation. The Journal of Urology. 1993 Aug; 150(2 Part 1): 310-2. doi: 10.1016/S0022-5347(17)35468-X.

Mitchell T, Kumar P, Reddy T, Wood KD, Knight J, Assimos DG et al. Dietary Oxalate and Kidney Stone Formation. American Journal of Physiology-Renal Physiology. 2019 Mar; 316(3): F409-13. doi: 10.1152/ajprenal.00373.2018.

Siener R. Nutrition and Kidney Stone Disease. Nutrients. 2021 Jun; 13(6): 1917. doi: 10.3390/nu13061917.

Taylor EN, Stampfer MJ, Curhan GC. Obesity, Weight Gain, and the Risk of Kidney Stones. Journal of the American Medical Association. 2005 Jan; 293(4): 455-62. doi: 10.1001/jama.293.4.455.

Scotland KB, Armas-Phan M, Dominique G, Bayne D. Social Determinants of Kidney Stone Disease: The Impact of Race, Income and Access On Urolithiasis Treatment and Outcomes. Urology. 2022 May; 163: 190-5. doi: 10.1016/j.urology.2021.08.037.