Cardiovascular Risk Factors Associated with Mitral Annular Calcification in a Non-Rheumatic Population: Cardiovascular Risk Factors

Mahboob ur Rehman; Muhammad Faisal; Anwar Ali; Mohmmad Iqbal; Asma Rauf; Amjad Abrar

doi:10.54393/pjhs.v5i09.2035

Authors

Mahboob ur Rehman Department of Cardiology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Muhammad Faisal Department of Community Medicine, Gomal Medical College, Dera Ismail Khan, Pakistan
Anwar Ali Department of Cardiology, Kulsum International Hospital, Islamabad, Pakistan
Mohmmad Iqbal Department of Cardiac Surgery, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Asma Rauf Department of Cardiology, Bilal Hospital, Rawalpindi, Pakistan
Amjad Abrar Department of Cardiology, Gomal Medical College, Dera Ismail Khan, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i09.2035

Keywords:

Echocardiography, Mitral Annular Calcification, Non-Rheumatic Population, Hypertension

Abstract

Mitral Annular Calcification (MAC), cardiovascular disease marker was common in non-rheumatic populations but was frequently disregarded in clinical evaluations. Objective: To MAC and to assess effect of these factors on cardiac function in non-rheumatic adult population. Methods: From September 2022 to August 2023, we conducted this cross-sectional study at Cardiac Center, Pakistan institute of medical sciences Islamabad that included 182 adults aged 50 years and older. We evaluated the patient's clinical history, demographic data and echocardiographic and laboratory results. The association between the presence of MAC and cardiovascular risk factors (age, hypertension, diabetes, dyslipidemia, smoking, obesity and chronic renal disease) was analyzed using logistic regression. Echocardiographic data were used to provide insight into cardiac function. Results: The prevalence of MAC was substantially correlated with hypertension (OR = 2.30), diabetes (OR = 2.00), dyslipidemia (OR = 1.75) and obesity (OR = 1.07). Also, smoking demonstrated a significant correlation with MAC. In comparison to those without MAC, individuals with MAC exhibited substantially lower ejection fractions, increased left atrial diameters and impaired diastolic function, as indicated by cardiac function assessments. Conclusion: In non-rheumatic population, MAC was significantly associated with conventional cardiovascular risk factors, particularly hypertension and diabetes.

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