Clinical and Biochemical Parameters among Hemodialysis Patients Before and During the Month of Ramadan: Clinical and Biochemical Parameters among Hemodialysis Patients

Abdul Rehman Qureshi; Farah Ahmad; Syed Hassan Danish; Shafaq Fayyaz

doi:10.54393/pjhs.v6i3.2706

Authors

Abdul Rehman Qureshi Department of Nephrology, Memon Medical Institute Hospital, Karachi, Pakistan
Farah Ahmad Department of Medical Education, College of Physicians and Surgeons, Karachi, Pakistan
Syed Hassan Danish Department of Community Health Sciences, Ziauddin University, Karachi, Pakistan
Shafaq Fayyaz Department of Nephrology, Memon Medical Institute Hospital, Karachi, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v6i3.2706

Keywords:

Biochemical, Fasting, Hemodialysis, Parameters, Ramadan

Abstract

Ramadan fasting among hemodialysis patients is a complex issue in the Muslim world, with varying opinions and outcomes. Objectives: To evaluate clinical and biochemical parameters in hemodialysis patients before and after Ramadan. Methods: This quasi-experimental study was conducted in a private tertiary care hospital in Karachi from March to April 2024. Patients undergoing hemodialysis for more than three months were included, except those who did not consent. Participants were categorized into three groups: complete fasting, intermittent fasting, and non-fasting. Clinical and biochemical parameters were measured before and after Ramadan, including ultra-filtrate, dry weight, potassium, phosphorus, and albumin. Data were analyzed using SPSS version 27.0, with paired t-tests and significance set at p<0.05. Results: 132 patients participated (56.1% male, 43.9% female). Most (90.9%) did not fast, while 5.3% fasted continuously and 8.3% intermittently. Hypertension was the most common comorbidity (47.7%). Ultra-filtrate levels significantly increased in both male and female. Potassium levels rose significantly in female and in patients on thrice-weekly dialysis. Albumin levels declined across all groups. No significant changes were observed in dry weight or phosphorus levels. Conclusions: It was concluded that increased ultra-filtrate and potassium levels post-Ramadan, with albumin declining in most groups. However, the fasting group showed no significant changes, highlighting the need for group-specific monitoring in hemodialysis patients during Ramadan.

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