Frequency of Hyperuricemia In Patients Presenting with Acute Ischaemic Stroke: Hyperuricemia in Patients with Acute Ischaemic Stroke

Amjad  Iqbal; Zia  Ullah; Arshad  Iqbal; Qiam  Ud Din; Aneeqa  Waheed; Saeed Ur Rahman

doi:10.54393/pjhs.v4i02.457

Authors

Amjad Iqbal Department of Neurology, Lady Reading Hospital, Peshawar, Pakistan
Zia Ullah Department of Neurology, Lady Reading Hospital, Peshawar, Pakistan
Arshad Iqbal Department of Neurosurgery, Lady Reading Hospital, Peshawar, Pakistan
Qiam Ud Din District Headquarter Hospital Timergara, Dir Lower, Pakistan
Aneeqa Waheed Department of Neurology, Lady Reading Hospital, Peshawar, Pakistan
Saeed Ur Rahman Department of Nursing, University of Health Sciences, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i02.457

Keywords:

Hyperuricemia, Patients, Acute, Ischemic Stroke, Uric Acid

Abstract

Hyperuricemia refers to elevated serum uric acid concentration above the upper limit of normal. Objective: To determine hyperuricemia in patients presenting with acute ischemic stroke to the Neurology ward of Lady Reading Hospital, Peshawar. Methods: A total of 153 patients were observed to the frequency of hyperuricemia in patients presenting with acute ischemic stroke. Study design was cross sectional study which was conducted for the period of 6 months. The total Sample size was calculated by using WHO sample size calculator. It was calculated using the World Health Organization software. Results: A total of 153 patients were observed to the frequency of hyperuricemia in patients presenting with acute ischemic stroke. Mean age of study participants was 52.45±1.14 years. Distribution of hyperuricemia was 114(74.5%). Mean serum uric acid level among cases of acute ischemic stroke was 06.15 ± 01.91 mg/dl while the mean serum uric acid level among control group was 05.1 ± 01.4 mg/dl. The results were highly significant p-value < 0.0001. Conclusions: Serum uric acid levels can be used to predict stroke risk. Moreover, serum uric acid can be utilized to stratify risk following a stroke. Long-term prospective research is needed to determine the involvement of serum uric acid in ischemic stroke. A trial of serum uric acid reducing medications in stroke patients as well as those at high risk of stroke may also be worthwhile.

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