Frequency of Iron Deficiency Anemia and Its Association with Persistent Diarrhea, Weight and Parasitic Infestation in Children, 1-2 Years of Age in Semi-Rural Area of District Sialkot, Pakistan
Iron Deficiency Anemia and its Association
DOI:
https://doi.org/10.54393/pjhs.v4i03.460Keywords:
IDA, Persistent Diarrhea, Low Weight, Parasitic InfestationAbstract
Iron deficiency anemia (IDA) is a common health problem in Pakistan and persistent diarrhea under two years of age is one of its major reasons. Objectives: To determine the frequency of IDA among children 1-2 years of age and to find its association with persistent diarrhea and parasitic infestation. Methods: In this hospital-based study, 345 children 1-2 years of age visiting OPD of Tehsil Headquarter Hospital, with persistent diarrhea were included. Socio-demographic characteristics of children and their parents collected with the questionnaire while total body iron stores determined by checking Hemoglobin (Hb), Serum Ferritin and Total Iron Binding Capacity (TIBC) in the blood while parasitic infestation was determined by Ova and Cyst in the stool samples. Chi-square test was used to test association. Results: Out of total children, 55.9% children were bottle fed, weaning was started among 97.7% children at the age of 6 months, 44.9% had weight <8 kg, 53.0% children were anemic, had TIBC >450 µg/dl and serum ferritin level <7 ng/ml. The association of IDA with age, gender, mode of feeding, food allergies and vaccination history were significant while it was insignificant with persistent diarrhea and parasitic infestation. Conclusions: Study concluded that IDA was very frequent among children in less than 2 years of age and among contributing factors, lack of beast-feeding and diarrhea are important. Correlation was significant between IDA with age and feeding mode while association was insignificant with persistent diarrhea and parasitic infestation
References
Domello M and Hernell O. Iron-deiciency anaemia during the first two years of life. Scandinavian Journal of Nutrition 2002 Jan; 46(1): 20-30. doi: 10.1080/110264802753704091
McDonagh MS, Blazina I, Dana T, Cantor A, Bougatsos C. Screening and routine supplementation for iron deficiency anemia: a systematic review. Pediatrics. 2015 Apr; 135(4): 723-33. doi: 10.1542/peds.2014-3979
Kanchana M, Ahuja S, Nagaraj N. Prevalence and risk factors of anemia in under five-year-old children in children’s hospital. International Journal of Contemporary Pediatrics. 2018 Mar; 5(2): 499-502. doi: 10.18203/2349-3291.ijcp20180543
Habib MA, Black K, Soofi SB, Hussain I, Bhatti Z, Bhutta ZA, et al. Prevalence and predictors of iron deficiency anemia in children under five years of age in Pakistan, a secondary analysis of national nutrition survey data 2011–2012. PloS one 2016 May; 11(5): e0155051. doi: 10.1371/journal.pone.0155051
Ullah I, Zahid M, Sthanadar AA, Sthanadar IA, Ali PA, Khan MI, et al. Iron deficiency anemia in school age children in District Karak Khyber Pakhtunkhwa Province, Pakistan. Open Journal of Blood Diseases. 2014 Jun; 4(2): 1-7. doi: 10.4236/ojbd.2014.42002
Malik NA, Shah SA, Mashhadi SF. Evaluation of injectable iron sucrose therapy in children with iron deficiency anemia. Pakistan Armed Forces Medical Journal 2016 Oct; 66(5): 680-3.
Woldie H, Kebede Y, Tariku A. Factors associated with anemia among children aged 6–23 months attending growth monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia. Journal of Nutrition and Metabolism. 2015 Oct; 2015: 1-9. doi: 10.1155/2015/928632
Wangusi NL, Waudo JN, Mugendi BJ. Prevalence and determinants of iron-deficiency anaemia among children 6-23 Months attending Thika level-5 hospital, Kiambu County, Kenya. 2016 Nov; 1(6): 28-38.
Howard CT, de Pee S, Sari M, Bloem MW, Semba RD. Association of diarrhea with anemia among children under age five living in rural areas of Indonesia. Journal of Tropical Pediatrics. 2007 Aug; 53(4): 238-44. doi: 10.1093/tropej/fmm011
Histolytica E and Lamblia G. Demographics of Intestinal Parasitic Infections in Karachi: An Insight from Positive Stool Samples. Journal of Islamic International Medical College (JIIMC). 2016 Mar; 11(1): 20-3.
Abdel-Rasoul GM, El Bahnasy RE, El Shazly HM, Gabr HM, Abdel-Aaty NB. Epidemiology of iron-deficiency anemia among primary school children (6-11 years), Menoufia governorate, Egypt. Menoufia Medical Journal. 2015 Jul; 28(3): 663-9.
Ahmad MS, Farooq H, Maham SN, Qayyum Z, Waheed A, Nasir W. Frequency of anemia and iron deficiency among children starting first year of school life and their association with weight and height. Anemia. 2018 Apr; 2018: 1-5. doi: 10.1155/2018/8906258
Kassaw MW, Abebe AM, Tlaye KG, Zemariam AB, Abate BB. Prevalence and risk factors of intestinal parasitic infestations among preschool children in Sekota town, Waghimra zone, Ethiopia. BMC Pediatrics. 2019 Dec; 19(1): 1-0. doi: 10.1186/s12887-019-1774-2
Behrman RE, Kleigman RM, Arvin AM. Nelson Textbook of Paediatric: Iron deficiency anaemia. 1996; 15: 502
Zahid A, Shaukat A, Mahmood KT. Lactose Intolerance. Journal of Biomedical Sciences and Research. 2010; 2(4): 290-4.
Maroof S, Rehman MU, Mahmood H, Masood S, Mashhadi SF. Determinants of diarrhea in childern up to two years of age: in a tertiary care hospital, Rawalpindi. Pakistan Armed Forces Medical Journal (PAFMJ). 2018 Aug; 68(4): 893-98.
Ahmad MS, Husain Zaidi SA, Medhat N, Farooq H, Ahmad D, Nasir W. Frequency of underweight and stunting among children entering school in a small urban locality and their association with academic performance. Journal of Pakistan Medical Association. 2018 Jan; 68(1): 28-32.
Dagnew AB, Tewabe T, Miskir Y, Eshetu T, Kefelegn W, Zerihun K, et al. Prevalence of diarrhea and associated factors among under-five children in Bahir Dar city, Northwest Ethiopia, 2016: a cross-sectional study. BMC Infectious Diseases. 2019 Dec; 19: 1-7. doi: 10.1186/s12879-019-4030-3
ud Din Z, Pervez L, Amir A, Abbas M, Khan I, Iqbal Z, et al. Parasitic infections, malnutrition and anemia among preschool children living in rural areas of Peshawar, Pakistan. Nutrición Hospitalaria: Organo Oficial De La Sociedad Española De Nutrición Parenteral Y Enteral. 2018 Sep; 35(5): 1145-52. doi: 10.20960/nh.1685
Quadri F, Nasrin D, Khan A, Bokhari T, Tikmani SS, Nisar MI, et al. Health care use patterns for diarrhea in children in low-income periurban communities of Karachi, Pakistan. American Journal of Tropical Medicine Hygiene. 2013 Jul; 89(1 Suppl): 49-55. doi: 10.4269/ajtmh.12-0757
Murye JW. The prevalence of iron deficiency and the associated factors in children aged 6-59 months in central equatoria state, Juba-south Sudan (Doctoral dissertation, University of Nairobi). 2014. Available at: http://erepository.uonbi.ac.ke/handle/11295/74344
Nyeko R, Kalyesubula I, Mworozi E, Bachou H. Lactose intolerance among severely malnourished children with diarrhoea admitted to the nutrition unit, Mulago hospital, Uganda. BMC Pediatrics. 2010 Dec; 10(1): 1-9. doi: 10.1186/1471-2431-10-31
Chandyo RK, Ulak M, Adhikari RK, Sommerfelt H, Strand TA. Prevalence of iron deficiency and anemia among young children with acute diarrhea in Bhaktapur, Nepal. InHealthcare. 2015 Jul: 3(3): 593-606. doi: 10.3390/healthcare3030593
Darlan DM, Ananda FR, Sari MI, Arrasyid NK, Sari DI. Correlation between iron deficiency anemia and intestinal parasitic infection in school-age children in Medan. InIOP Conference Series: Earth and Environmental Science 2018 Mar; 125(1): 012059. doi: 10.1088/1755-1315/125/1/012059
Javaid MK, Latif N, Alam AN. Prevalence of intestinal parasitic infestations among children. Journal of Rawalpindi Medical College. 2016 Sep; 20(3): 216-8.
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