Incidence of the Atrial Fibrillation in Patients with Chronic Obstructive Pulmonary Disease (COPD) in Sindh, Pakistan

Atrial Fibrillation in Patients with Chronic Obstructive Pulmonary Disease

Authors

  • Arshad Hussain Laghari Department of Biochemistry, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Majid Ali Abbasi Department of Biochemistry, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Akhtar Hussain Samoo Department of Physiology, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Shafi Muhammad Khuhawar Department of Pulmonology, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Nazakat Hussain Memon Department of Biochemistry, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Ajeet Kumar Department of Pharmacology, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
  • Naila Sarki Department of Biochemistry, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i02.498

Keywords:

Atrial Fibrillation, Chronic Obstructive Pulmonary Disease, Arrhythmia

Abstract

Chronic obstructive pulmonary disease (COPD) is a major public health problem and leading cause of death globally. COPD fails to receive adequate attention from the health care community and government officials, with these concerns in mind we designed our study. Objective: To find out the incidence of atrial fibrillation in patients with COPD. Methods: A cross-sectional study was conducted from 12th February 2019 to August, 2020 at the Department of Pulmonology, Ghulam Muhammad Maher Medical College teaching Hospital, Sukkur. N=150 patients with chronic obstructive lung disease were involved in this study. The Criterion for the selection of patients for the study was those patients who was a diagnosed case of COPD. The exclusion criteria were known asthmatic patients and the case of restrictive lung diseases; history of ischemic heart disease, already on cardiac medication, patients with hyperthyroidism whereas the percentages, mean and Standard deviation were computed for study variables. Results: During One year and six months phase, patients who had COPD for > 3-Year duration were explored and study. The mean, SD for age (years) of citizens of Sindh Rural and Urban was 59.52 ± 7.81. Regarding gender, male 64 % and female 36 % individuals whereas the Atrial Fibrillation (AF) was identified in 62 % patients of COPD. Conclusions: High risk of AF has been identified among the COPD patients in Pakistani Populace. Hypertension and CHF among the COPD patients were notable as self-sufficient hazard features for new beginning of AF.

References

Rabe KF and Watz H. Chronic obstructive pulmonary disease. Lancet. 2017 May; 389(10082): 1931-40. doi: 10.1016/S0140-6736(17)31222-9.

Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. American Journal of Respiratory and Critical Care Medicine. 2001 Apr; 163(5): 1256-76. doi: 10.1164/ajrccm.163.5.2101039.

Fabbri LM, Romagnoli M, Corbetta L, Casoni G, Busljetic K, Turato G, et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 2003 Feb; 167(3): 418-24. doi: 10.1164/rccm.200203-183OC.

January CT, Wann LS, Calkins H, Chen LY, Cigarroa JE, Cleveland Jr JC, et al. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in collaboration with the Society of Thoracic Surgeons. Circulation. 2019 Jul; 140(2): e125-51. doi: 10.1161/CIR.0000000000000665.

January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Journal of the American College of Cardiology. 2014 Dec; 64(21): e1-76. doi: 10.1016/j.jacc.2014.03.022.

Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991 Aug; 22(8): 983-8. doi: 10.1161/01.STR.22.8.983.

Magnani JW, Rienstra M, Lin H, Sinner MF, Lubitz SA, McManus DD, et al. Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation. 2011 Nov; 124(18): 1982-93. doi: 10.1161/CIRCULATIONAHA.111.039677.

Konecny T, Park JY, Somers KR, Konecny D, Orban M, Soucek F, et al. Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias. The American Journal of Cardiology. 2014 Jul; 114(2): 272-7. doi: 10.1016/j.amjcard.2014.04.030.

Mendez-Bailon M, Lopez-de-Andres A, de Miguel-Diez J, de Miguel-Yanes JM, Hernández-Barrera V, Munoz-Rivas N, et al. Chronic obstructive pulmonary disease predicts higher incidence and in hospital mortality for atrial fibrillation. An observational study using hospital discharge data in Spain (2004–2013). International Journal of Cardiology. 2017 Jun; 236: 209-15. doi: 10.1016/j.ijcard.2017.02.017.

Chahal H, Heckbert SR, Barr RG, Bluemke DA, Jain A, Habibi M, et al. Ability of reduced lung function to predict development of atrial fibrillation in persons aged 45 to 84 years (from the Multi-Ethnic Study of Atherosclerosis-Lung Study). The American Journal of Cardiology. 2015 Jun; 115(12): 1700-4. doi: 10.1016/j.amjcard.2015.03.018.

Buch P, Friberg J, Scharling H, Lange P, Prescott E. Reduced lung function and risk of atrial fibrillation in the Copenhagen City Heart Study. European Respiratory Journal. 2003 Jun; 21(6): 1012-6. doi: 10.1183/09031936.03.00051502.

Shibata Y, Watanabe T, Osaka D, Abe S, Inoue S, Tokairin Y, Igarashi A, Yamauchi K, Kimura T, Kishi H, Aida Y. Impairment of pulmonary function is an independent risk factor for atrial fibrillation: the Takahata study. International journal of medical sciences. 2011 Aug; 8(7): 514-22. doi: 10.7150/ijms.8.514.

Terzano C, Romani S, Conti V, Paone G, Oriolo F, Vitarelli A. Atrial fibrillation in the acute, hypercapnic exacerbations of COPD. European Review for Medical and Pharmacological Sciences. 2014 Oct; 18(19): 2908-17.

Li J, Agarwal SK, Alonso A, Blecker S, Chamberlain AM, London SJ, et al. Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Circulation. 2014 Mar; 129(9): 971-80. doi: 10.1161/CIRCULATIONAHA.113.004050.

Ganga HV, Nair SU, Puppala VK, Miller WL. Risk of new-onset atrial fibrillation in elderly patients with the overlap syndrome: a retrospective cohort study. Journal of Geriatric Cardiology: JGC. 2013 Jun; 10(2): 129. doi: 10.3969/j.issn.1671-5411.2013.02.001.

Kucher N and Goldhaber SZ. Cardiac biomarkers for risk stratification of patients with acute pulmonary embolism. Circulation. 2003 Nov; 108(18): 2191-4. doi: 10.1161/01.CIR.0000100687.99687.CE.

Söhne M, Ten Wolde M, Büller HR. Biomarkers in pulmonary embolism. Current Opinion in Cardiology. 2004 Nov; 19(6): 558-62. doi: 10.1097/01.hco.0000138991.82347.0e.

Kaczyñska A, Pelsers MM, Bochowicz A, Kostrubiec M, Glatz JF, Pruszczyk P. Plasma heart-type fatty acid binding protein is superior to troponin and myoglobin for rapid risk stratification in acute pulmonary embolism. Clinica Chimica Acta. 2006 Sep; 371(1-2): 117-23. doi: 10.1016/j.cca.2006.02.032.

Binder L, Pieske B, Olschewski M, Geibel A, Klostermann B, Reiner C, et al. N-terminal pro–brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation. 2005 Sep; 112(11): 1573-9. doi: 10.1161/CIRCULATIONAHA.105.552216.

Tulevski II, ten Wolde M, van Veldhuisen DJ, Mulder JW, van der Wall EE, Büller HR, et al. Combined utility of brain natriuretic peptide and cardiac troponine T may improve rapid triage and risk stratification in normotensive patients with pulmonary embolism. International Journal of Cardiology. 2007 Mar; 116(2): 161-6. doi: 10.1016/j.ijcard.2006.03.030.

Becattini C, Vedovati MC, Agnelli G. Prognostic value of troponins in acute pulmonary embolism: a meta-analysis. Circulation. 2007 Jul; 116(4): 427-33. doi: 10.1161/CIRCULATIONAHA.106.680421.

Bajaj A, Saleeb M, Rathor P, Sehgal V, Kabak B, Hosur S. Prognostic value of troponins in acute nonmassive pulmonary embolism: a meta-analysis. Heart & Lung. 2015 Jul; 44(4): 327-34. doi: 10.1016/j.hrtlng.2015.03.007.

Stevenson IH, Roberts-Thomson KC, Kistler PM, Edwards GA, Spence S, Sanders P, et al. Atrial electrophysiology is altered by acute hypercapnia but not hypoxemia: implications for promotion of atrial fibrillation in pulmonary disease and sleep apnea. Heart rhythm. 2010 Sep; 7(9): 1263-70. doi: 10.1016/j.hrthm.2010.03.020.

Chen CY and Liao KM. The impact of atrial fibrillation in patients with COPD during hospitalization. International Journal of Chronic Obstructive Pulmonary Disease. 2018 Jul; 13: 2105-12. doi: 10.2147/COPD.S166534.

Goldhaber SZ. Assessing the prognosis of acute pulmonary embolism: tricks of the trade. Chest. 2008 Feb; 133(2): 334-6. doi: 10.1378/chest.07-2464.

Puls M, Dellas C, Lankeit M, Olschewski M, Binder L, Geibel A, et al. Heart-type fatty acid-binding protein permits early risk stratification of pulmonary embolism. European Heart Journal. 2007 Jan; 28(2): 224-9. doi: 10.1093/eurheartj/ehl405.

Leung AN, Müller NL, Pineda PR, FitzGerald JM. Primary tuberculosis in childhood: radiographic manifestations. Radiology. 1992 Jan; 182(1): 87-91. doi: 10.1148/radiology.182.1.1727316.

Hussey G, Chisholm T, Kibel M. Miliary tuberculosis in children: a review of 94 cases. The Pediatric Infectious Disease Journal. 1991 Nov; 10(11): 832-6. doi: 10.1097/00006454-199111000-00008.

Kabra SK, Lodha R, Seth V. Some current concepts on childhood tuberculosis. Indian Journal of Medical Research. 2004 Oct; 120: 387-97.

Van Dyck P, Vanhoenacker FM, Van den Brande P, De Schepper AM. Imaging of pulmonary tuberculosis. European Radiology. 2003 Aug; 13: 1771-85. doi: 10.1007/s00330-002-1612-y.

Kim WS, Moon WK, Kim IO, Lee HJ, Im JG, Yeon KM, et al. Pulmonary tuberculosis in children: evaluation with CT. AJR. American Journal of Roentgenology. 1997 Apr; 168(4): 1005-9. doi: 10.2214/ajr.168.4.9124105.

Koh WJ, Jeong YJ, Kwon OJ, Kim HJ, Cho EH, Lew WJ, et al. Chest radiographic findings in primary pulmonary tuberculosis: observations from high school outbreaks. Korean Journal of Radiology. 2010 Dec; 11(6): 612-7. doi: 10.3348/kjr.2010.11.6.612.

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Published

2023-02-28
CITATION
DOI: 10.54393/pjhs.v4i02.498
Published: 2023-02-28

How to Cite

Hussain Laghari, A. ., Ali Abbasi, M. ., Hussain Samoo, A. ., Muhammad Khuhawar, S. ., Hussain Memon, N. ., Kumar, A. ., & Sarki, N. . (2023). Incidence of the Atrial Fibrillation in Patients with Chronic Obstructive Pulmonary Disease (COPD) in Sindh, Pakistan: Atrial Fibrillation in Patients with Chronic Obstructive Pulmonary Disease. Pakistan Journal of Health Sciences, 4(02), 145–149. https://doi.org/10.54393/pjhs.v4i02.498

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