The Risk Factors of Intestinal Perforation Associated with Peritonitis

Risk Factors of Intestinal Perforation

Authors

  • Imran Younas Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Alia Naseer Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Usra Naeem Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Muzamil Irshad Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Muhammad Umair Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Fazeelat Akram Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Maria Fayyaz Department of Health Professional Technologies, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Manzoor Ahmad Naeem Al Baha Hospital, Kingdom of Saudi Arabia

DOI:

https://doi.org/10.54393/pjhs.v4i02.574

Keywords:

Intestinal perforation, Appendicitis, Fever

Abstract

Perforation is known as an abnormal opening in an empty organ. It is copied from the Latin word perforatus, meaning “to bore through.” In western world the estimated frequency of intestinal perforation ranges from 0.6% to 4.9%. Objective: To find out the risk factors of intestinal perforation associated with peritonitis. Methods: It was a cross-sectional study and data was collected from February 2022 to July 2022. Data was collected from, DHQ Teaching Hospital Gujranwala and Social Security Hospital Multan chungi Lahore. Calculated sample size was 50 based on prevalence (0.68%) of intestinal perforation through an online sample size calculator (CI 95% and margin of error=0.09%). Patients of both genders with age limit of 10-60 years and patients presenting with perforation peritonitis were included in this study. Patients with Post-operative peritonitis and Immuno-compromised patients were excluded from study. Patient demographic information was collected. For demographic variables and risk factors of intestinal perforation descriptive analysis was used. Ethical approval has been obtained from concerned department and statistical analysis was done using SPSS version 24. Results: Out of 50 patients 38% were female and 62% were male. Major risk factors for intestinal perforation were Appendicitis (32%), Trauma (26%), Abdominal distension (24%) and Intestinal obstruction (20%). Conclusion: This study concludes that intestinal perforation is commonly seen between the age group of 21-30 years. Common risk factors of intestinal perforation are fever, appendicitis, trauma, abdominal distension, followed by intestinal obstruction, ascites and infection. The most commonly found perforation is duodenal perforation.

 

References

Meena LN, Jain S, Bajiya P. Gastrointestinal perforation peritonitis in India: A study of 442 cases. Saudi Surgical Journal. 2017 Sep; 5(3): 116-121. doi: 10.4103/ssj.ssj_33_17

Nadkarni FM, Shetly SD, Kagzi RS. Small-bowel perforation. A study of 32 cases. Archives Surgery 1981; 116: 53-57. doi: 10.1001/archsurg.1981.01380130033008

Gedik E, Girgin S, Taçyıldız IH, Akgün Y. Risk factors affecting morbidity in typhoid enteric perforation. Langenbeck's archives of surgery. 2008 Nov; 393(6): 973-7. doi: 10.1007/s00423-007-0244-8

Jindal N, Arora S, Pathania S. Fungal culture positivity in patients with perforation peritonitis. Journal of Clinical and Diagnostic Research: JCDR. 2015 Jun; 9(6). doi: 10.7860/JCDR/2015/13189.6050

Shahid MH, Khan FI, Askri Z, Asad A, Alam MA, Ali D, et al. One Year of Experience Managing Peritonitis Secondary to Gastrointestinal Perforation at a Tertiary Care Hospital: A Retrospective Analysis. Cureus. 2022 Apr; 14(4). doi: 10.7759/cureus.23966

Jacobs B, Jawad A, Fattah Z. Pneumatosis intestinalis and intestinal perforation in a patient receiving tocilizumab. Archives of Rheumatology. 2018 Sep; 33(3): 372. doi: 10.5606/ArchRheumatol.2018.6668

Joshi P, Poudel R, Chandra K. Mannheim Peritonitis Index (MPI) score as a predictor of outcome in patients with secondary peritonitis. Journal of Universal College of Medical Sciences. 2016; 4(2): 6-9. doi: 10.3126/jucms.v4i2.19083

Afridi SP, Malik F, Ur-Rahman S, Shamim S, Samo KA. Spectrum of perforation peritonitis in Pakistan: 300 cases Eastern experience. World Journal of Emergency Surgery. 2008 Dec; 3(1): 1-5. doi: 10.1186/1749-7922-3-31

Chakma SM, Singh RL, Parmekar MV, Singh KG, Kapa B, Sharatchandra KH, et al. Spectrum of perforation peritonitis. Journal of clinical and diagnostic research. 2013 Nov; 7(11): 2518. doi: 10.7860/JCDR/2013/5768.3596

Jain U, Chauhan A, Gupta J, Gupta AK. Evaluation of Boey scoring in predicting morbidity and mortality in peptic ulcer perforation peritonitis. International Journal of Surgery Science. 2021; 5(3): 41-3. doi: 10.33545/surgery.2021.v5.i3a.735

Kallely M, Panchabhai S, Nichkaode P, Rayani H, Teja JR, Patil D. Perforation peritonitis: a clinical profile and management. Sri Lanka Journal of Surgery. 2020 Apr 30; 38(1). doi: 10.4038/sljs.v38i1.8649

Kabongo KM, Erzingatsian K. Early postoperative complications associated with perforation. 2021.

Hafner J, Tuma F, Hoilat GJ, Marar O. Intestinal perforation. InStatPearls. 2021 Nov.

Endo Y, Abe Y, Kawano S, Ando T, Sakamoto K, Tamura N. The association between absence of abdominal pain and mortality in lower intestinal perforation in patients with autoimmune rheumatic diseases. BioMed research international. 2019 Feb; 2019. doi: 10.1155/2019/5381453

Sakaguchi T, Tokuhara K, Nakatani K, Kon M. Laparoscopic management for spontaneous jejunal perforation caused by nonspecific ulcer: A case report. International journal of surgery case reports. 2017 Jan; 39: 309-12. doi: 10.1016/j.ijscr.2017.08.048

Bali RS, Verma S, Agarwal PN, Singh R, Talwar N. Perforation peritonitis and the developing world. International Scholarly Research Notices. 2014 Apr; 2014. doi: 10.1155/2014/105492

Gupta SK, Gupta R, Singh G, Gupta S. Perforation peritonitis: a two-year experience. Jk Science. 2010 Jul; 12(3): 141.

Jhobta RS, Attri AK, Kaushik R, Sharma R, Jhobta A. Spectrum of perforation peritonitis in India-review of 504 consecutive cases. World journal of Emergency surgery. 2006 Dec; 1(1): 1-4. doi: 10.1186/1749-7922-1-26

Gupta S and Kaushik R. Peritonitis-the Eastern experience. World journal of emergency surgery. 2006 Dec; 1(1): 1-6. doi: 10.1186/1749-7922-1-13

Bano F, Malik S, Soomro I. Secondary Bacterial Peritonitis. Journal of Surgery Pakistan. 2017 Oct; 22: 4. doi: 10.21699/jsp.22.4.6

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Published

2023-02-28
CITATION
DOI: 10.54393/pjhs.v4i02.574
Published: 2023-02-28

How to Cite

Younas, I., Naseer, A., Naeem, U., Irshad, M., Umair, M., Akram, F., Fayyaz, M., & Naeem, M. A. (2023). The Risk Factors of Intestinal Perforation Associated with Peritonitis: Risk Factors of Intestinal Perforation. Pakistan Journal of Health Sciences, 4(02), 150–153. https://doi.org/10.54393/pjhs.v4i02.574

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