Age-related Increase in Incidence of Postoperative Atrial Fibrillation Following Coronary Artery Bypass Grafting (CABG) Surgery

Incidence of Postoperative Atrial Fibrillation

Authors

  • Salman Ahmed Department of Cardiac Surgery, Dow International Medical College, Dow University of Health Sciences, Karachi, Pakistan
  • Riffat Tanveer Department of Cardiac Surgery, Dow International Medical College, Dow University of Health Sciences, Karachi, Pakistan
  • Masroor Sharfi Dow Institute of Cardiology, Dow University of Health Sciences, Karachi, Pakistan
  • Adnan Ali Khahro Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, Pakistan
  • Shakir Lakhani Tabba Heart Institute, Karachi, Pakistan
  • Asadullah Khan Dr Ruth K. M Pfau Civil Hospital, Karachi, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i06.848

Keywords:

Atrial Fibrillation, Coronary Artery Bypass Grafting, Arrhythmia

Abstract

Atrial Fibrillation (AF) is one of the common arrhythmias after coronary artery bypass grafting (CABG) mostly occurs within 2 to 4 days. The advanced age is one of the important risk factors. Objective: To determine the frequency of Postoperative Atrial Fibrillation (POAF) in patients age between 30-65 years who underwent elective CABG Surgery. Methods: One hundred and thirty-seven Adult patients of either sex between age of 30 to 65 years with three vessel coronary artery disease underwent elective CABG surgery were included in our study. It was descriptive cross-sectional study, conducted at Tabba Heart Institute, Karachi, from December 2021 to June 2022. Postoperatively daily EKG was performed for the evidence of POAF. Results: One hundred and thirty-seven patients, between age group of 30-65 years among them 115 (84%) were male & 22 (16%) were females with mean age of patients 55.91years were included in our study. Post-Operative Atrial Fibrillation (POAF) was observed in 12.4%, out of whom 76.5% were male while 23.5% were female. The mean day of onset of POAF was 2.38 days. The relationship between increasing age groups and AF was found to be statistically significant i.e. p-value 0.04. There is significant difference between age groups and maximum incidence of POAF were found in above 60 years. Conclusions: In our study frequency of POAF was found in 12.4 %with mean age of participants was found to be 55.91 ± 6.5 years.

 

 

Objective: To determine the frequency of Postoperative Atrial Fibrillation (POAF) in patients age between 30-65 years who underwent elective CABG Surgery.

 

Methodology: One hundred and thirty seven Adult patients of either sex between age of 30 to 65 years with three vessel coronary artery disease underwent elective CABG surgery were included in our study. It was descriptive cross-sectional study, conducted at Tabba Heart Institute, Karachi, from December 2021 to June 2022. Postoperatively daily EKG was performed for the evidence of POAF.

 

RESULT: One hundred and thirty seven patients, between age group of 30-65 years among them 115 (84%) were male & 22 (16%) were females with mean age of patients 55.91years were included in our study. Post-Operative Atrial Fibrillation (POAF) was observed in 12.4%, out of whom 76.5% were male while 23.5% were female. The mean day of onset of POAF was 2.38 days. The relationship between increasing age groups and AF was found to be statistically significant i.e. p-value 0.04. There is significant difference between age groups and maximum incidence of POAF were found in above 60 years.

 

CONCLUSION:  In our study frequency of POAF was found in 12.4 %with mean age of participants was found to be 55.91 + 6.5 years.

References

Taha A, Nielsen SJ, Bergfeldt L, Ahlsson A, Friberg L, Björck S, et al. New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Outcome: A Population-Based Nationwide Study from the SWEDEHEART Registry. Journal of American Heart Association. 2021 Jan; 10(1): e017966. doi: 10.1161/JAHA.120.017966. DOI: https://doi.org/10.1161/JAHA.120.017966

Higgs M, Sim J, Traynor V. Incidence and risk factors for new-onset atrial fibrillation following coronary artery bypass grafting: A systematic review and meta-analysis. Intensive and Critical Care Nursing. 2020 Jun; 60: 102897. doi: 10.1016/j.iccn.2020.102897. DOI: https://doi.org/10.1016/j.iccn.2020.102897

Jannati M. Atrial Fibrillation Post Coronary Artery Graft Surgery: A Review of Literature. International Journal of General Medicine. 2019 Nov; 12: 415-20. doi: 10.2147/IJGM.S227761. DOI: https://doi.org/10.2147/IJGM.S227761

Seo EJ, Hong J, Lee HJ, Son YJ. Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review. BMC Cardiovascular Disorders. 2021 Dec; 21(1): 1-1. doi: 10.1186/s12872-021-02224-x. DOI: https://doi.org/10.1186/s12872-021-02224-x

Camci S, Ari S, Karakus A, Ari H, Taner T. The predictive value of the combined systolic-diastolic index for atrial fibrillation after coronary artery bypass surgery. Echocardiography. 2020 Aug; 37(8): 1177-83. doi: 10.1111/echo.14806. DOI: https://doi.org/10.1111/echo.14806

Dobrev D, Aguilar M, Heijman J, Guichard JB, Nattel S. Postoperative atrial fibrillation: mechanisms, manifestations and management. Nature Reviews Cardiology. 2019 Jul; 16(7): 417-36. doi: 10.1038/s41569-019-0166-5. DOI: https://doi.org/10.1038/s41569-019-0166-5

Hernández-Leiva E, Alvarado P, Dennis RJ. Postoperative Atrial Fibrillation: Evaluation of its Economic Impact on the Costs of Cardiac Surgery. Brazilian Journal of Cardiovascular Surgery. 2019 Mar; 34(2): 179-86. doi: 10.21470/1678-9741-2018-0218. DOI: https://doi.org/10.21470/1678-9741-2018-0218

Phan K, Ha HS, Phan S, Medi C, Thomas SP, Yan TD. New-onset atrial fibrillation following coronary bypass surgery predicts long-term mortality: a systematic review and meta-analysis. European Journal of Cardiothoracic Surgery. 2015 Dec ;48(6): 817-24. DOI: https://doi.org/10.1093/ejcts/ezu551

Shimony A, Afilalo J, Flynn AW, Langleben D, Agnihotri AK, Morin JF, et al. Usefulness of right ventricular dysfunction to predict new-onset atrial fibrillation following coronary artery bypass grafting. The American Journal of Cardiology. 2014 Mar; 113(6): 913-8. doi: 10.1016/j.amjcard.2013.12.031. DOI: https://doi.org/10.1016/j.amjcard.2013.11.048

Sedrakyan A, Zhang H, Treasure T, Krumholz HM. Recursive partitioning–based preoperative risk stratification for atrial fibrillation after coronary artery bypass surgery. American Heart Journal. 2006 Mar; 151(3): 720-4. doi: 10.1016/j.ahj.2005.11.010. DOI: https://doi.org/10.1016/j.ahj.2005.05.010

Engin M and Aydın C. Investigation of the effect of HATCH score and coronary artery disease complexity on atrial fibrillation after on-pump coronary artery bypass graft surgery. Medical Principles and Practice. 2021 Feb; 30(1): 45-51. doi: 10.1159/000508726. DOI: https://doi.org/10.1159/000508726

Gu S, Su PX, Liu Y, Yan J, Zhang XT, Wang TY. Low-dose amiodarone for the prevention of atrial fibrillation after coronary artery bypass grafting in patients older than 70 years. Chinese Medical Journal. 2009 Dec; 122(24): 2928-32.

El-Chami MF, Kilgo P, Thourani V, Lattouf OM, Delurgio DB, Guyton RA, et al. New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology. 2010 Mar; 55(13): 1370-6. doi: 10.1016/j.jacc.2010.01.006. DOI: https://doi.org/10.1016/j.jacc.2009.10.058

Malik A, Bangash SK, Haq MI, Rehman M, Hussain M. Atrial fibrillation following coronary artery bypass graft surgery. Journal of Postgraduates Medical Institute. 2006 Apr; 20(2): 143-8.

Echahidi N, Pibarot P, O’Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. Journal of the American College of Cardiology. 2008 Feb; 51(8): 793-801. doi: 10.1016/j.jacc.2007.10.049. DOI: https://doi.org/10.1016/j.jacc.2007.10.043

Kaw RK, Hernandez AV, Masood I, Saliba W, Gillinov AM, Blackstone EH. Short- and long-term mortality in new onset atrial fibrillation after coronary artery bypass graft: a sytematic review and meta-analysis. Journal of the American College of Cardiology. 2010 Mar; 55(10S): A8-E76. doi: 10.1016/j.jtcvs.2010.03.063. DOI: https://doi.org/10.1016/S0735-1097(10)60077-0

Ngaage DL, Schaff HV, Mullany CJ, Sundt III TM, Dearani JA, Barnes S, et al. Does preoperative atrial fibrillation influence early and late outcomes of coronary artery bypass grafting? The Journal of Thoracic and Cardiovascular Surgery. 2007 Jan; 133(1): 182-9. doi: 10.1016/j.jtcvs.2006.09.081. DOI: https://doi.org/10.1016/j.jtcvs.2006.09.021

Mariscalco G, Klersy C, Zanobini M, Banach M, Ferrarese S, Borsani P, et al. Atrial fibrillation after isolated coronary surgery affects late survival. Circulation. 2008 Oct; 118(16): 1612-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.108.777789

Davies MJ and Pomerance A. Pathology of atrial fibrillation in man. British Heart Journal. 1972 May; 34(5): 520. DOI: https://doi.org/10.1136/hrt.34.5.520

Perrier S, Meyer N, Minh TH, Announe T, Bentz J, Billaud P, et al. Predictors of atrial fibrillation after coronary artery bypass grafting: a Bayesian analysis. The Annals of Thoracic Surgery. 2017 Jan; 103(1): 92-7. doi: 10.1016/j.athoracsur.2016.06.089. DOI: https://doi.org/10.1016/j.athoracsur.2016.05.115

Ismail MF, El-Mahrouk AF, Hamouda TH, Radwan H, Haneef A, Jamjoom AA. Factors influencing postoperative atrial fibrillation in patients undergoing on-pump coronary artery bypass grafting, single center experience. Journal of Cardiothoracic Surgery. 2017 May; 12(1): 40. doi: 10.1186/s13019-017-0609-1. DOI: https://doi.org/10.1186/s13019-017-0609-1

Downloads

Published

2023-06-30
CITATION
DOI: 10.54393/pjhs.v4i06.848
Published: 2023-06-30

How to Cite

Ahmed , S. ., Tanveer, R. ., Sharfi , M., Ali Khahro, A. ., Lakhani , S. ., & Khan, A. . (2023). Age-related Increase in Incidence of Postoperative Atrial Fibrillation Following Coronary Artery Bypass Grafting (CABG) Surgery: Incidence of Postoperative Atrial Fibrillation. Pakistan Journal of Health Sciences, 4(06), 155–158. https://doi.org/10.54393/pjhs.v4i06.848

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)