The New Spectrum of Plasmodium Vivax Malaria Severity: A Single-Center Experience

New Spectrum of Plasmodium Vivax Malaria Severity

Authors

  • Naveed Iqbal Department of Medicine, Medical Teaching Institution, Lady Reading Hospital, Peshawar, Pakistan
  • Ahmad Al Ibad Department of Pathology, Bannu Medical College, Bannu, Pakistan
  • Momina Haq Department of Physiology, Peshawar Medical College, Peshawar, Pakistan
  • Faisal Shahzad Department of Pathology, Frontier Medical College, Abbottabad, Pakistan
  • Ambreen Gul Department of Chemical Pathology, Peshawar Medical College, Riphah International University, Islamabad, Pakistan
  • Saira Nasr Malik Department of Pathology, Khyber Medical College, Khyber Teaching Hospital, Peshawar, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i09.2019

Keywords:

Plasmodium, Malaria, Thrombocytopenia, Hypoglycemia

Abstract

Plasmodium vivax malaria, once considered a benign and self-limiting disease, has emerged as a significant public health concern, with increasing reports of severe and even fatal cases. Objective: To evaluate the clinical severity and complications associated with Plasmodium vivax malaria in patients in Peshawar. Methods: A descriptive cross-sectional study was conducted at Lady Reading Hospital, Peshawar, for about two months. A total of 160 patients diagnosed with Plasmodium vivax malaria were enrolled. Participants were divided into two groups based on platelet count. Laboratory tests, including complete blood count, liver function tests, and Renal Function Tests were performed. Data were analyzed using SPSS version 20.0 , An Independent sample t-test was used to assess the significant difference between the two groups with statistical significance set at p<0.05. Results: A total of 165 patients were included in the study. In the severe thrombocytopenia group (<100,000/µL), there were 23 cases of anemia, jaundice (n=25), acute renal failure (n=7), cerebral malaria (n=2), seizures (n=1) and hypoglycemia (n=1). In the less severe thrombocytopenia group (>100,000/µL), there were 14 cases of anemia, jaundice (n=17), and acute renal failure (n=2). The blood glucose level (p=0.37), systolic blood pressure (p=0.18) and pulse rate (p=0.21) revealed no significant differences between the two groups. Conclusions: It was concluded that severe thrombocytopenia in P. vivax malaria was associated with more severe clinical manifestations, with a few cases requiring transfusions. Patients with less severe thrombocytopenia had fewer complications

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Published

2024-09-30
CITATION
DOI: 10.54393/pjhs.v5i09.2019
Published: 2024-09-30

How to Cite

Iqbal, N., Ibad, A. A., Haq, M., Shahzad, F., Gul, A., & Malik, S. N. (2024). The New Spectrum of Plasmodium Vivax Malaria Severity: A Single-Center Experience: New Spectrum of Plasmodium Vivax Malaria Severity. Pakistan Journal of Health Sciences, 5(09), 60–64. https://doi.org/10.54393/pjhs.v5i09.2019

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