Impact of Passive Smoking on Low Birth Weight among Pregnant Women in Active Labor: Passive Smoking on Low Birth Weight among Women in Active Labor

Ayesha Akhter; Aasma Hanif; Shagufta Jabbar; Mariyam Humaira; Aneela Khan; Attyia Rashid; Rafia Ali; Muneera Azim Chaudhry

doi:10.54393/pjhs.v5i10.2261

Authors

Ayesha Akhter Department of Obstetrics and Gynecology, Sahara Medical College, Narowal, Pakistan
Aasma Hanif Department of Obstetrics and Gynecology, University College of Medicine and Dentistry, Lahore, Pakistan
Shagufta Jabbar Department of Obstetrics and Gynecology, Punjab Employees Social Security Institute, Lahore, Pakistan
Mariyam Humaira Department of Obstetrics and Gynecology, Service Hospital, Lahore, Pakistan
Aneela Khan Department of Obstetrics and Gynecology, Kettering General Hospital/University, Northampton Shire, United Kingdom
Attyia Rashid Department of Obstetrics and Gynecology, University College of Medicine and Dentistry, Lahore, Pakistan
Rafia Ali Department of Obstetrics and Gynecology, Fatima Memorial Hospital, College of Medicine and Dentistry, Lahore, Pakistan
Muneera Azim Chaudhry Department of Obstetrics and Gynecology, Rafiq Medical College, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i10.2261

Keywords:

Low Birth Weight, Passive Smoking, Pregnancy, Birth Outcomes, Active Labor

Abstract

Passive smoking during pregnancy, also called second-hand smoke exposure or environmental tobacco smoke, pretenses a substantial threat to fetal and maternal health. Objectives: To evaluate the association between passive smoking exposure and adverse birth outcomes in low birth weight in pregnant women. Methods: A case-control study was conducted at the Department of Obstetrics and Gynecology, Sughra Shafi Medical Complex, Narowal, from January 2024 to June 2024, involving 150 pregnant women presenting in active labour. Non-probability consecutive sampling techniques were used. Passive smoker’s women were assessed for adverse birth outcomes like low birth weight. Data were analyzed using SPSS-23.0. The chi-square test was used to calculate associations between exposure and outcomes. Odds ratios were calculated with 95% confidence intervals, with p≤0.05 considered statistically significant. Results: 56.7% of the study population was exposed to passive smoking, of which 48.7% delivered Low Birth Weight infants as compared to 25.3% preterm births. Passive Smoker women had significantly higher odds of preterm births (OR: 2.7, p<0.05) and low birth weight (OR: 2.08, p<0.05). Additional risk factors for low birth weight included abnormal BMI (OR: 2.79, p<0.05), multiparity (OR: 6.43, p<0.05), and maternal age over 30 years (OR: 5.7, p<0.05). Conclusions: It was concluded that a significant association between passive smoking and adverse birth outcomes was found, especially Low Birth Weight and preterm. The risks were markedly higher among women over age 30 years, those with multiparity and abnormal BMI. Results highlight the need for directed interventions to decrease passive smoking exposure in pregnant women.

References

Mahmoodabad SS, Karimiankakolaki Z, Kazemi A, Mohammadi NK, Fallahzadeh H. Exposure to Secondhand Smoke in Iranian Pregnant Women at Home and ahe Related Factors. Tobacco Prevention & Cessation. 2019 Feb; 5: 7. doi: 10.18332/tpc/104435.

Qu Y, Chen S, Pan H, Zhu H, Yan C, Zhang S et al. Exposure to Tobacco Smoke and Stillbirth: A National Prospective Cohort Study in Rural China. Journal of Epidemiology and Community Health. 2020 Apr; 74(4): 315-20. doi: 10.1136/jech-2019-213290.

Hamadneh S and Hamadneh J. Active and Passive Maternal Smoking During Pregnancy and Birth Outcomes: A Study from A Developing Country. Annals of Global Health. 2021 Dec; 87(1): 122. doi: 10.5334/aogh.3384.

Delcroix MH, Delcroix-Gomez C, Marquet P, Gauthier T, Thomas D, Aubard Y. Active or Passive Maternal Smoking Increases the Risk of Low Birth Weight or Preterm Delivery: Benefits of Cessation and Tobacco Control Policies. Tobacco-Induced Diseases. 2023 May; 21: 72. doi: 10.18332/tid/156854.

Ramadani M, Utomo B, Achadi EL, Gunardi H. Prenatal Secondhand Smoke Exposure: Correlation Between Nicotine in Umbilical Cord Blood and Neonatal Anthropometry. Osong Public Health and Research Perspectives. 2019 Aug; 10(4): 234-9. doi: 10.24171/j.phrp.2019.10.4.06.

Delcroix-Gomez C, Delcroix MH, Jamee A, Gauthier T, Marquet P, Aubard Y. Fetal Growth Restriction, Low Birth Weight, and Preterm Birth: Effects of Active or Passive Smoking Evaluated by Maternal Expired CO at Delivery, Impacts of Cessation at Different Trimesters. Tobacco-Induced Diseases. 2022 Aug; 20: 70. doi: 10.18332/tid/152111.

Cahyani NI, Delim AA, Hartoko RA. The Effect of Passive Smoking during Pregnancy on Low Birth Weight. Green Medical Journal. 2023 Dec; 5(3): 111-20. doi: 10.5334/aogh.3384.

Sagawa Y, Ogawa T, Matsuyama Y, Nakagawa Kang J, Yoshizawa Araki M, Unnai Yasuda Y et al. Association between Smoking During Pregnancy and Short Root Anomaly in Offspring. International Journal of Environmental Research and Public Health. 2021 Nov; 18(21): 11662. doi: 10.3390/ijerph182111662.

Zhao L, Chen L, Yang T, Wang L, Wang T, Zhang S et al. Parental Smoking and the Risk of Congenital Heart Defects in Offspring: An Updated Meta-Analysis of Observational Studies. European Journal of Preventive Cardiology. 2020 Aug; 27(12): 1284-93. doi: 10.1177/2047487319831367.

Yasmeen T, Sultana R, Khatoon T, Riaz S. Effect of Passive Smoking During Pregnancy on Birth Weight of Neonates. Pakistan Journal of Medical and Health Sciences. 2022 Jun; 16(05): 724-. doi: 10.53350/pjmhs22165724.

Zhang Q, Zhang ZC, He XY, Liu ZM, Wei GH, Liu X. Maternal Smoking During Pregnancy and the Risk of Congenital Urogenital Malformations: A Systematic Review and Meta-Analysis. Frontiers in Pediatrics. 2022 Oct; 10: 973016. doi: 10.3389/fped.2022.973016.

Adibelli D and Kirca N. The Relationship Between Gestational Active and Passive Smoking and Early Postpartum Complications. The Journal of Maternal-Fetal and Neonatal Medicine. 2020 Jul; 33(14): 2473-9. doi: 10.1080/14767058.2020.1763294.

Ye ZH, Chen HS, Zhang ZC, Wang X, Liu X, Wei GH. Parental Smoking and Risk of Hypospadias: An Updated Meta-Analysis of Observational Studies. Frontiers in Pediatrics. 2023 Feb; 11: 1003037. doi: 10.3389/fped.2023.1003037.

Moore BF, Starling AP, Magzamen S, Harrod CS, Allshouse WB, Adgate JL et al. Fetal Exposure to Maternal Active and Secondhand Smoking with Offspring Early-Life Growth in the Healthy Start Study. International Journal of Obesity. 2019 Apr; 43(4): 652-62. doi: 10.1038/s41366-018-0238-3.

Wang R, Sun T, Yang Q, Yang Q, Wang J, Li H et al. Low Birthweight of Children Is Positively Associated with Mother’s Prenatal Tobacco Smoke Exposure in Shanghai: A Cross-Sectional Study. BioMed Central Pregnancy and Childbirth. 2020 Dec; 20: 1-9. doi: 10.1186/s12884-020-03307-x.

Lewandowska M, Sajdak S, Więckowska B, Manevska N, Lubiński J. The Influence of Maternal BMI on Adverse Pregnancy Outcomes in Older Women. Nutrients. 2020 Sep; 12(9): 2838. doi: 10.3390/nu12092838.

Devaguru A, Gada S, Potpalle D, Eshwar MD, Purwar D. The Prevalence of Low Birth Weight Among Newborn Babies and Its Associated Maternal Risk Factors: A Hospital-Based Cross-Sectional Study. Cureus. 2023 May; 15(5). doi: 10.7759/cureus.38587.

Rang NN, Hien TQ, Chanh TQ, Thuyen TK. Preterm Birth and Secondhand Smoking During Pregnancy: A Case-Control Study from Vietnam. PLoS One. 2020 Oct; 15(10): e0240289. doi: 10.1371/journal.pone.0240289.

Banerjee S, Deacon A, Suter MA, Aagaard KM. Understanding the Placental Biology of Tobacco Smoke, Nicotine, and Marijuana (THC) Exposures During Pregnancy. Clinical Obstetrics and Gynecology. 2022 Jun; 65(2): 347-59. doi: 10.1097/GRF.0000000000000691.

Deng C, Pu J, Deng Y, Xie L, Yu L, Liu L et al. Association Between Maternal Smoke Exposure and Congenital Heart Defects from A Case-Control Study in China. Scientific Reports. 2022 Sep; 12(1): 14973. doi: 10.1038/s41598-022-18909-y.