Comparison of the oral health status of type-1 Diabetes Mellitus and healthy children: A comparative study
Oral Health Status of Type-1 Diabetes Mellitus and Healthy Children
DOI:
https://doi.org/10.54393/pjhs.v3i05.252Keywords:
Keywords: Oral health, Children, Type-1 diabetes mellitus, Caries, Periodontal healthAbstract
Being a chronic systemic disease type-1 Diabetes Mellitus (DM) affect both physical health and oral health of an individual. As a dentist, a thorough comprehension of the pathology, clinical manifestations, and therapy of orofacial diseases in DM patients is necessary to provide the best care possible to the patients. Objective: The purpose of this study was to observe the impact of type-1 DM on dental health. Methods: A questionnaire-based study was conducted on 264 subjects (132 type-1 DM children, 132 healthy children) attending Children’s hospital PIMS, Islamabad. The oral health status of type-1 DM and healthy children was compared using WHO oral health assessment form for children and Fox’s questionnaire was used. Comparisons between the oral health status of type-1 DM children with healthy children was done by Mann-Whitney U test. A comparison of oral health status among Type-1 DM children based on glycemic control was done by one-way ANOVA test. Results: Females were in majority in both groups as compared to males. The frequency of oral diseases was more in type-1 DM children as compared to healthy children. A significant statistical difference p < 0.005 was found between the oral health status of both groups. Based on glycemic control among type-1 DM children, there was no significant statistical difference found for DMFT, halitosis, and xerostomia however, there was a significant statistical difference found for BOP and mucosal lesion. Conclusions: Type-1 DM children are more prone to developing oral diseases as compared to healthy children.
References
Kharroubi AT and Darwish HM. Diabetes mellitus: The epidemic of the century. World Journal of Diabetes. 2015 Jun; 6(6):850-67. doi: 10.4239/wjd. v6. i6.850.
Choudhury H, Pandey M, Hua CK, Mun CS, Jing JK, Kong L, et al. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. Journal of Traditional and Complementary Medicine. 2017 Nov; 8(3):361-376. doi: 10.1016/j.jtcme.2017.08.012.
Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of Type 2 Diabetes - Global Burden of Disease and Forecasted Trends. Journal of Epidemiology and Global Health. 2020 Mar; 10(1):107-111. doi: 10.2991/jegh.k.191028.001.
Patterson C, Guariguata L, Dahlquist G, Soltész G, Ogle G, Silink M. Diabetes in the young - a global view and worldwide estimates of numbers of children with type 1 diabetes. Diabetes Research and Clinical Practice. 2014 Feb; 103(2):161-75. doi: 10.1016/j.diabres.2013.11.005.
Shera AS, Jawad F, Maqsood A. Prevalence of diabetes in Pakistan. Diabetes Research and Clinical Practice. 2007 May;76(2):219-22. doi: 10.1016/j.diabres.2006.08.011.
Basit A, Fawwad A, Baqa K. Diabetes Registry of Pakistan. Pakistan Journal of Medical Sciences. 2020 Apr;36(3):578-580. doi: 10.12669/pjms.36.3.1877.
Paul S, Ali A, Katare R. Molecular complexities underlying the vascular complications of diabetes mellitus - A comprehensive review. Journal of Diabetes and Its Complications. 2020 Aug; 34(8):107613. doi: 10.1016/j.jdiacomp.2020.107613.
Chen J, Zeng H, Ouyang X, Zhu M, Huang Q, Yu W, et al. The incidence, risk factors, and long-term outcomes of acute kidney injury in hospitalized diabetic ketoacidosis patients. BMC Nephrology. 2020 Feb; 21(1):48. doi: 10.1186/s12882-020-1709-z.
Alwafi H, Alsharif AA, Wei L, Langan D, Naser AY, Mongkhon P, et al. Incidence and prevalence of hypoglycaemia in type 1 and type 2 diabetes individuals: A systematic review and meta-analysis. Journal of Diabetes Research. 2020 Dec; 170:108522. doi: 10.1016/j.diabres.2020.108522.
Lee R, Wong TY, Sabanayagam C. Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss. Eye. 2015 Sep; 2:17. doi: 10.1186/s40662-015-0026-2.
Ufuoma C, Ngozi JC, Kester AD, Godwin YD. Prevalence and risk factors of microalbuminuria among type 2 diabetes mellitus: A hospital-based study from, Warri, Nigeria. Sahel Medical Journal. 2016 Jan;19(1):16.
Sifuentes-Franco S, Padilla-Tejeda DE, Carrillo-Ibarra S, Miranda-Díaz AG. Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy. International Journal of Endocrinology. 2018 Apr; 2018:1875870. doi: 10.1155/2018/1875870
Verhulst MJL, Loos BG, Gerdes VEA, Teeuw WJ. Evaluating All Potential Oral Complications of Diabetes Mellitus. Frontiers in Endocrinology. 2019 Feb; 10:56. doi: 10.3389/fendo.2019.00056.
Sadeghi R, Taleghani F, Mohammadi S, Zohri Z. The Effect of Diabetes Mellitus Type I on Periodontal and Dental Status. Journal of Clinical and Diagnostic Research. 2017 Jul; 11(7):ZC14-ZC17. doi: 10.7860/JCDR/2017/25742.10153.
Wan R, Weissman JP, Grundman K, Lang L, Grybowski DJ, Galiano RD. Diabetic wound healing: The impact of diabetes on myofibroblast activity and its potential therapeutic treatments. Wound Repair Regen. 2021 Jul; 29(4):573-581. doi: 10.1111/wrr.12954
Afakova MS and Murtazaev SS. Improving the efficiency of caries prevention due to the timing of the eruption and mineralization of permanent teeth in children environmental problems of the regions of the republic of uzbekistan. middle european scientific bulletin. 2020 Nov; 6:1-4.
Saini R, Al-Maweri SA, Saini D, Ismail NM, Ismail AR. Oral mucosal lesions in non-oral habit diabetic patients and association of diabetes mellitus with oral precancerous lesions. Journal of diabetes research. 2010 Sep; 89(3):320-6. doi: 10.1016/j.diabres.2010.04.016.
Ismail AF, McGrath CP, Yiu CK. Oral health of children with type 1 diabetes mellitus: A systematic review. Journal of diabetes research.2015 Jun;108(3):369-81. doi: 10.1016/j.diabres.2015.03.003.
Coelho ASEDC, Carneiro AS, Pereira VF, Paula AP, Macedo AP, Carrilho EVP. Oral Health of Portuguese Children with Type 1 Diabetes: The Journal of clinical pediatric dentistry. 2018; 42(3):231-235. doi: 10.17796/1053-4628-42.3.12.
Rafatjou R, Razavi Z, Tayebi S, Khalili M, Farhadian M. Dental health status and hygiene in children and adolescents with type 1 diabetes mellitus. Journal of research in health sciences. 2016; 16(3):122.
Ferizi L, Dragidella F, Spahiu L, Begzati A, Kotori V. The Influence of Type 1 Diabetes Mellitus on Dental Caries and Salivary Composition. International dental journal. 2018 Oct; 2018:5780916. doi: 10.1155/2018/5780916.
Siudikiene J, Machiulskiene V, Nyvad B, Tenovuo J, Nedzelskiene I. Dental caries increments and related factors in children with type 1 diabetes mellitus. Caries Research. 2008; 42(5):354-62. doi: 10.1159/000151582.
Hilt A and Filipińaska-Skapska R. Problemy zdrowotne jamy ustnej dzieci z cukrzyca typu 1 [Oral health problems in type 1 diabetic children]. Przegl Lek. 2007; 64(2):78-80.
Babu KLG, Subramaniam P, Kaje K. Assessment of dental caries and gingival status among a group of type 1 diabetes mellitus and healthy children of South India - a comparative study. Journal of Pediatric Endocrinology and Metabolism. 2018 Dec; 31(12):1305-1310. doi: 10.1515/jpem-2018-0335
Giuca MR, Pasini M, Giuca G, Caruso S, Necozione S, Gatto R. Investigation of periodontal status in type 1 diabetic adolescents. European journal of pediatrics. 2015 Dec; 16(4):319-23.
Al-Khabbaz AK, Al-Shammari KF, Hasan A, Abdul-Rasoul M. Periodontal health of children with type 1 diabetes mellitus in Kuwait: a case-control study. Medical Principles and Practice. 2013; 22(2):144-9. doi: 10.1159/000342624.
Javed F, Sundin U, Altamash M, Klinge B, Engström PE. Self-perceived oral health and salivary proteins in children with type 1 diabetes. Journal of oral rehabilitation. 2009 Jan; 36(1):39-44. doi: 10.1111/j.1365-2842.2008.01895. x.
Silva MF, Barbosa KG, Pereira JV, Bento PM, Godoy GP, Gomes DQ. Prevalence of oral mucosal lesions among patients with diabetes mellitus types 1 and 2. Anais Brasileiros de Dermatologia. 2015 Feb; 90(1):49-53. doi: 10.1590/abd1806-4841.20153089.
Babatzia A, Papaioannou W, Stavropoulou A, Pandis N, Kanaka-Gantenbein C, Papagiannoulis L, et al. Clinical and microbial oral health status in children and adolescents with type 1 diabetes mellitus. International journal of dentistry. 2020 Apr; 70(2):136-144. doi: 10.1111/idj.12530.
Hoseini A, Mirzapour A, Bijani A, Shirzad A. Salivary flow rate and xerostomia in patients with type I and II diabetes mellitus. Electron Physician. 2017 Sep; 9(9):5244-5249. doi: 10.19082/5244.
López-Pintor RM, Casañas E, González-Serrano J, Serrano J, Ramírez L, et al. Xerostomia, Hyposalivation, and Salivary Flow in Diabetes Patients. Journal of diabetes research. 2016; 4372852. doi: 10.1155/2016/4372852.
Pappa E, Vastardis H, Rahiotis C. Chair-side saliva diagnostic tests: An evaluation tool for xerostomia and caries risk assessment in children with type 1 diabetes. Journal of dentistry. 2020 Feb; 93:103224. doi: 10.1016/j.jdent.2019.103224.
Kogawa EM, Grisi DC, Falcão DP, Amorim IA, Rezende TM, da Silva IC, et al. Impact of glycemic control on oral health status in type 2 diabetes individuals and its association with salivary and plasma levels of chromogranin A. Archives of oral biology. 2016 Feb; 62:10-9. doi: 10.1016/j.archoralbio.2015.11.005.
Javed F, Thafeed Alghamdi AS, Mikami T, Mehmood A, Ahmed HB, et al. Effect of glycemic control on self-perceived oral health, periodontal parameters, and alveolar bone loss among patients with prediabetes. Journal of periodontology. 2014 Feb; 85(2):234-41. doi: 10.1902/jop.2013.130008
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