Demographic characterization of  patients suffering from tuberculosis visiting tertiary care hospital’ Lahore

Misbah Arshad; Muniba Tariq; Maimoona Ashfaq; Sidra Khalid; Hafsa Kamran; Maria Aslam; Zainab Sharmeen

doi:10.54393/pjhs.v2i02.27

Authors

Misbah Arshad
Muniba Tariq University Institute of Dietetics and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Maimoona Ashfaq University Institute of Dietetics and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Sidra Khalid
Hafsa Kamran University Institute of Dietetics and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Maria Aslam University Institute of Dietetics and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Zainab Sharmeen University Institute of Dietetics and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v2i02.27

Keywords:

Demographic characterization, Tuberculosis, Pulmonary tuberculosis, Extra pulmonary tuberculosis, CAT treatment

Abstract

Tuberculosis is a contagious disease, primarily caused by bacteria specifically Mycobacterium tuberculosis, M. bwis, or M. africanum. TB is a communicable disease involving impoverishment, mal-nutrition and poor immune system. Morbidity and mortality of TB are measured very high in developing countries Objective: To assess the demographic characterization of tuberculosis patients visiting Tertiary Care Hospital Lahore Methods: A cross-sectional study was carried out at the chest department of Sir Ganga Ram Hospital, Lahore during November-2018 to January-2019. A sample of 100 tuberculosis patients was selected through non-probability convenient sampling technique. Patients were assessed through pre-tested questionnaire. SPSS version 21.0 was used for data analysis Results: Among 100 participants, 55 patients were female and 45 patients were male. The prevalence of tuberculosis is more in female than male. 24% male and 22% female were suffering from pulmonary TB. The mean age of the patients was 35 years. Geographically 59% were from urban areas; 42% patients belonged to lower class. BMI of 47% patients were normal; 39% patients were underweight; 10% patients were overweight and 4%patients were obese. 60% patients were living joint family and 59% were from urban areas Conclusion: It was concluded that the prevalence of tuberculosis is more common in urban or congested areas. Socioeconomic status also has a significant impact on the development of disease.

References

Babu S. Biomarkers for treatment monitoring in tuberculosis: a new hope. EBioMedicine. 2017 Dec 1;26:13-4.

Churchyard G, Kim P, Shah NS, Rustomjee R, Gandhi N, Mathema B, Dowdy D, Kasmar A, Cardenas V. What we know about tuberculosis transmission: an overview. The Journal of infectious diseases. 2017 Nov 3;216(suppl_6):S629-35. https://doi.org/10.1093/infdis/jix362.

Nguyen L. Antibiotic resistance mechanisms in M. tuberculosis: an update. Archives of toxicology. 2016 Jul;90(7):1585-604. DOI 10.1007/s00204-016-1727-6.

Reid MJ, Arinaminpathy N, Bloom A, Bloom BR, Boehme C, Chaisson R, Chin DP, Churchyard G, Cox H, Ditiu L, Dybul M. Building a tuberculosis-free world: The Lancet Commission on tuberculosis. The Lancet. 2019 Mar 30;393(10178):1331-84.

Kiazyk S, Ball TB. Tuberculosis (TB): Latent tuberculosis infection: An overview. Canada Communicable Disease Report. 2017 Mar 2;43(3-4):62. https://dx.doi.org/10.14745%2Fccdr.v43i34a01.

Yoon C, Dowdy DW, Esmail H, MacPherson P, Schumacher SG. Screening for tuberculosis: time to move beyond symptoms. The Lancet Respiratory Medicine. 2019 Mar 1;7(3):202-4. https://doi.org/10.1016/S2213-2600(19)30039-6.

World Health Organization. BCG vaccine: WHO position paper, February 2018–recommendations. Vaccine. 2018 Jun 7;36(24):3408-10. https://doi.org/10.1016/j.vaccine.2018.03.009.

Kehbila J, Ekabe CJ, Aminde LN, Noubiap JJ, Fon PN, Monekosso GL. Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon. Infectious Diseases of Poverty. 2016 Dec;5(1):1-8. DOI 10.1186/s40249-016-0145-6

Chakaya J, Khan M, Ntoumi F, Aklillu E, Fatima R, Mwaba P, Kapata N, Mfinanga S, Hasnain SE, Katoto PD, Bulabula AN. Global Tuberculosis Report 2020–Reflections on the Global TB burden, treatment and prevention efforts. International Journal of Infectious Diseases. 2021 Dec 1;113:S7-12. https://doi.org/10.1016/j.ijid.2021.02.107.

Petkar KC, Chavhan S, Kunda N, Saleem I, Somavarapu S, Taylor KM, Sawant KK. Development of novel octanoyl chitosan nanoparticles for improved rifampicin pulmonary delivery: optimization by factorial design. AAPS PharmSciTech. 2018 May;19(4):1758-72. DOI: 10.1208/s12249-018-0972-9.

Mendis S, Davis S, Norrving B. Organizational update: the world health organization global status report on noncommunicable diseases 2014; one more landmark step in the combat against stroke and vascular disease. Stroke. 2015 May;46(5):e121-2. https://doi.org/10.1161/STROKEAHA.115.008097.

World Health Organization. Global tuberculosis report 2013. World Health Organization; 2013.

Waitt CJ, Squire SB. A systematic review of risk factors for death in adults during and after tuberculosis treatment. The International journal of tuberculosis and lung disease. 2011 Jul 1;15(7):871-85. https://doi.org/10.5588/ijtld.10.0352.

Gurung LM, Bhatt LD, Karmacharya I, Yadav DK. Dietary practice and nutritional status of tuberculosis patients in Pokhara: a cross sectional study. Frontiers in nutrition. 2018 Aug 16;5:63. https://doi.org/10.3389/fnut.2018.00063.

Lönnroth K, Williams BG, Cegielski P, Dye C. A consistent log-linear relationship between tuberculosis incidence and body mass index. International journal of epidemiology. 2010 Feb 1;39(1):149-55. https://doi.org/10.1093/ije/dyp308.

AL-Auqbi TF. Nutritional and Epidemiological Characteristics of Iraqi TB Patients. IRAQI JOURNALOF COMMUNITY MEDICINE. 2007;20(3).

Walzl G, McNerney R, du Plessis N, Bates M, McHugh TD, Chegou NN, Zumla A. Tuberculosis: advances and challenges in development of new diagnostics and biomarkers. The Lancet Infectious Diseases. 2018 Jul 1;18(7):e199-210. https://doi.org/10.1016/S1473-3099(18)30111-7.

Lönnroth K, Williams BG, Cegielski P, Dye C. A consistent log-linear relationship between tuberculosis incidence and body mass index. International journal of epidemiology. 2010 Feb 1;39(1):149-55. https://doi.org/10.1093/ije/dyp308.

Oxlade O, Huang CC, Murray M. Estimating the impact of reducing under-nutrition on the tuberculosis epidemic in the central eastern states of India: a dynamic modeling study. PloS one. 2015 Jun 5;10(6):e0128187. https://doi.org/10.1371/journal.pone.0128187.

Samuel B, Tyson Volkmann SC, Mukhopadhay S, MejoJose KM, Kumar AM, Oeltmann JE, Parija S, Prabhakaran AO, Moonan PK, Chadha VK. Relationship between nutritional support and tuberculosis treatment outcomes in West Bengal, India. Journal of tuberculosis research. 2016 Dec;4(4):213. https://dx.doi.org/10.4236%2Fjtr.2016.44023.

Al-Otaibi F, El Hazmi MM. Extra-pulmonary tuberculosis in Saudi Arabia. Indian Journal of Pathology and Microbiology. 2010 Apr 1;53(2):227.

Yang Z, Kong Y, Wilson F, Foxman B, Fowler AH, Marrs CF, Cave MD, Bates JH. Identification of risk factors for extrapulmonary tuberculosis. Clinical infectious diseases. 2004 Jan 15;38(2):199-205. https://doi.org/10.1086/380644.

Sreeramareddy CT, Panduru KV, Verma SC, Joshi HS, Bates MN. Comparison of pulmonary and extrapulmonary tuberculosis in Nepal-a hospital-based retrospective study. BMC infectious diseases. 2008 Dec;8(1):1-7. http://www.biomedcentral.com/1471-2334/8/8.

Bates MN, Khalakdina A, Pai M, Chang L, Lessa F, Smith KR. Risk of tuberculosis from exposure to tobacco smoke: a systematic review and meta-analysis. Archives of internal medicine. 2007 Feb 26;167(4):335-42. doi:10.1001/archinte.167.4.335.