Efficacy Of Using Cationorm and Systane Eye Drops on Post-Lasik Dry Eye
Cationorm and Systane Eye Drops on Post-Lasik Dry Eye
DOI:
https://doi.org/10.54393/pjhs.v3i04.86Keywords:
LASIK, Dry eye, Systane eye drop, Cationorm eye dropAbstract
LASIK is famous procedure for correcting refractive errors. The post-LASIK dry eye is very common. Systane and cationorm eye drops are good for post-LASIK dry eye. Objectives: To evaluate and compare the efficacy of Cationorm and Systane eye drops and assess the effect on asthenopic symptoms post-LASIK dry eye. Methods: A Qusai experimental study design was used. This study included 80 patients with the age of 20 to 35 years. Data were collected at Al Qasim Eye Care. 40 patients were treated with cationorm; and other were treated with Systane on post-LASIK dry eye. After using cationorm and systane eye drops assessment of dry eye was measured by TBUT. Patients came for follow ups at 2nd day, 15th day and 1 month after the LASIK procedure was done. Statistical analysis was done by applying Mann Whitney U test, Friedman’s two-way test, Cochran’s test and chi square test. Results: The mean value and standard deviation of Systane and cationorm eye drop recorded at the baseline were 10.00, ± 0.00, 10.00 ± 0.00, after 2nd day it was 8.08 ± 1.163, 8.48 ± 0.987, after 15 days 8.93 ± 2.485, 12.30 ± 1.713, and 1 month 9.05 ± 2.417, 12.93 ± 1.745 respectively. There was a significant effect on post-LASIK dry eye after using Systane and Cationorm eye drop with p<0. 001.Comparison of systane and Cationorm eye drops with asthenopic symptoms on post-LASIK dry eye showed cationorm is better than the systane eye drops. Conclusions: Cationorm showed more significant results as compared to systane eye drops and cationorm gave faster relief from asthenopic symptoms on post-LASIK dry eye
References
Bibliowicz J, Tittle RK, Gross JM. Toward a better understanding of human eye disease insights from the zebrafish, Danio rerio. Progression in Molecular Biology and Translational Science. 2011; 100:287-330. doi: 10.1016/B978-0-12-384878-9.00007-8
Sridhar MS. Anatomy of cornea and ocular surface. Indian Journal of Ophthalmology. 2018 Feb; 66(2):190-194. doi: 10.4103/ijo.IJO_646_17
Schmitt AJ, Moreira ATR, Filho FAK, Schmitt FP. Corneal Posterior Curvature Changes After Phacoemulsification Cataract Surgery with 2.75 mm Corneal Incision. Medical Hypothesis, Discovery and Innovation in Ophthalmology. 2019; 8(2):110-115
Seitz B, Langenbucher A, Torres F, Behrens A, Suárez E. Changes of posterior corneal astigmatism and tilt after myopic laser in situ keratomileusis. Cornea. 2002 Jul; 21(5):441-6. doi: 10.1097/00003226-200207000-00001
Gab-Alla AA. Is the axial length a risk factor for post-LASIK myopic regression? Graefes Archive for Clinical and Experimental Ophthalmology. 2021 Mar; 259(3):777-786. doi: 10.1007/s00417-020-04990-4
Pasquali T and Krueger R. Topography-guided laser refractive surgery. Current Opinion in Ophthalmology. 2012 Jul; 23(4):264-8. doi: 10.1097/ICU.0b013e328354adf0
Zhao PF, Hu YB, Wang Y, Fu CY, Zhang J, Zhai CB. Comparison of correcting myopia and astigmatism with SMILE or FS-LASIK and postoperative higher-order aberrations. International Journal of Ophthalmology. 2021 Apr; 14(4):523-528. doi: 10.18240/ijo.2021.04.07
Galor A, Patel S, Small LR, Rodriguez A, Venincasa MJ, Valido SE, et al. Pregabalin failed to prevent dry eye symptoms after laser-assisted in situ keratomileusis (LASIK) in a randomized pilot study. Journal of clinical medicine. 2019 Sep; 8(9):1355. doi: 10.3390/jcm8091355
Sakhnov SN, Yanchenko SV, Malyshev AV, Kalantaevskaya YA, Ismaylova RA, Ehieva EM, et al. Dry eye epidemiology in patients before refractive operations. Ophthalmology in Russia. 2018 Mar; 15(1):92-101. doi: 10.18008/1816-5095-2018-1-92-101
Ousler G, Devries DK, Karpecki PM, Ciolino JB. An evaluation of Retaine™ ophthalmic emulsion in the management of tear film stability and ocular surface staining in patients diagnosed with dry eye. Clinical Ophthalmology. 2015 Feb; 9:235-43. doi: 10.2147/OPTH.S75297
O'Keefe M and Nolan L. LASIK surgery in children. British Journal of Ophthalmology. 2004 Jan; 88(1):19-21. doi: 10.1136/bjo.88.1.19
Wilkinson JM, Cozine EW, Kahn AR. Refractive Eye Surgery: Helping Patients Make Informed Decisions About LASIK. American Family Physician. 2017 May; 95(10):637-644
Pflugfelder SC and de Paiva CS. The Pathophysiology of Dry Eye Disease: What We Know and Future Directions for Research. Ophthalmology. 2017 Nov; 124(11S):S4-S13. doi: 10.1016/j.ophtha.2017.07.010
Shoja MR and Besharati MR. Dry eye after LASIK for myopia: Incidence and risk factors. European Journal of Ophthalmology. 2007 Feb; 17(1):1-6. doi: 10.1177/112067210701700101
Durrie D and Stahl J. A randomized clinical evaluation of the safety of Systane Lubricant Eye Drops for the relief of dry eye symptoms following LASIK refractive surgery. Clinical Ophthalmology. 2008 Dec; 2(4):973-9. doi: 10.2147/opth.s4475
Seitz B, Torres F, Langenbucher A, Behrens A, Suárez E. Posterior corneal curvature changes after myopic laser in situ keratomileusis. Ophthalmology. 2001 Apr; 108(4):666-72. doi: 10.1016/s0161-6420(00)00581-9
Das S, Garg P, Mullick R, Annavajjhala S. Keratitis following laser refractive surgery: Clinical spectrum, prevention and management. Indian Journal of Ophthalmology. 2020 Dec; 68(12):2813-2818. doi: 10.4103/ijo.IJO_2479_20
Fogagnolo P, Quisisana C, Caretti A, Marchina D, Dei Cas M, Melardi E, et al. Efficacy and Safety of VisuEvo® and Cationorm® for the Treatment of Evaporative and Non-Evaporative Dry Eye Disease: A Multicenter, Double-Blind, Cross-Over, Randomized Clinical Trial. Clinical Ophthalmology. 2020 Jun; 14:1651-1663. doi: 10.2147/OPTH.S258081
Elsayed AN. Comparison between Autologous Serum Eye Drops and Punctal Occlusion for Treatment of Dry Eye Syndrome. The Egyptian Journal of Hospital Medicine. 2022 Jan; 86(1):350-7. doi: 10.21608/ejhm.2022.212034
Grob D, Childs M, Piaton JM. Comparative study of 0.1% hyaluronic acid versus 0.5% carboxymethylcellulose in patients with dry eye associated with moderate keratitis or keratoconjunctivitis. Clinical Ophthalmology. 2018 Jun; 12:1081-1088. doi: 10.2147/OPTH.S161578
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