Gender Based Differences in COVID-19 Patients

Amber Hassan; Humaira Waseem; SIdra Khalid; SamiUllah Mumtaz

doi:10.54393/pjhs.v2i01.38

Authors

Amber Hassan Department of Systems Medicine, University of Milan, Milan, Italy
Humaira Waseem Fatima Jinnah Medical University, Lahore, Pakistan
SIdra Khalid Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
SamiUllah Mumtaz Department of Medicine, Mayo Hospital, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v2i01.38

Keywords:

COVID-19, Gender, Diseased, Co-morbid, Severity

Abstract

acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has become a worldwide public health emergency. COVID-19 symptoms include cough, sputum production, fever, myalgia, irregular heartbeat, dyspnea, headache, diarrhea, and a painful throat. Objective: To evaluate the gender-based differences among COVID patients. Methods: A total of 150 people took part in the cross-sectional study. The information was gathered using a self-structured questionnaire and non-probability convenient sampling. The subjects' written informed consents were obtained prior to the start of the study. The analysis of the data was done by using SPSS version 25.0. Results: The findings revealed that hypertension was the most common comorbidity among COVID-19 patients, followed by diabetes mellitus, especially in females. Males were more likely to have renal problems and asthma. The severity of the disease and gender had a significant relationship (p=0.001), according to the analysis. Conclusions: There was a strong link between gender and disease severity.

References

Lu R, Zhao X, Li J, Niu P, Yang B and Wu H et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8.

Chen N, Zhou M, Dong X, Qu J, Gong F and Han Y et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7.

Deng SQ and Peng HJ. Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China. J Clin Med. 2020;9(2):575. doi: 10.3390/jcm9020575.

Huang C, Wang Y, Li X, Ren L, Zhao J and Hu Y et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5.

Wang B, Li R, Lu Z and Huang Y. Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. Aging (Albany NY). 2020;12(7):6049-6057. doi: 10.18632/aging.103000.

Wu Z and McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239-1242. doi: 10.1001/jama.2020.2648.

Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX and Chong M et al. Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020;323(16):1612-1614. doi: 10.1001/jama.2020.4326.

Lesser IA and Nienhuis CP. The Impact of COVID-19 on Physical Activity Behavior and Well-Being of Canadians. Int J Environ Res Public Health. 2020;17(11):3899. doi:10.3390/ijerph17113899.

Wan S, Xiang Y, Fang W, Zheng Y, Li B and Hu Y et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020;92(7):797-806. doi: 10.1002/jmv.25783.

Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY and Loh J et al. Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA. 2020;323(15):1488-1494. doi: 10.1001/jama.2020.3204.

Ueyama H, Kuno T, Takagi H, Krishnamoorthy P, Vengrenyuk Y and Sharma SK et al. Gender Difference Is Associated With Severity of Coronavirus Disease 2019 Infection: An Insight From a Meta-Analysis. Crit Care Explor. 2020;2(6):e0148. doi:10.1097/CCE.0000000000000148.

Jansen A, Chiew M, Konings F, Lee CK and Ailan L. Sex matters - a preliminary analysis of Middle East respiratory syndrome in the Republic of Korea, 2015. Western Pac Surveill Response J. 2015;6(3):68-71. doi: 10.5365/WPSAR.2015.6.3.002.

Pérez-López FR, Tajada M, Savirón-Cornudella R, Sánchez-Prieto M, Chedraui P and Terán E. Coronavirus disease 2019 and gender-related mortality in European countries: A meta-analysis. Maturitas. 2020;141:59-62.

Ancochea J, Izquierdo JL, Savana COVID-19 Research Group and Soriano JB. Evidence of gender differences in the diagnosis and management of coronavirus disease 2019 patients: an analysis of electronic health records using natural language processing and machine learning. Journal of Women's Health. 2021;30(3):393-404. doi.org/10.1089/jwh.2020.8721.

Zhou Y, Yang Q, Chi J, Dong B, Lv W and Shen L et al. Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis. Int J Infect Dis. 2020;99:47-56. doi: 10.1016/j.ijid.2020.07.029.

Yang X, Yu Y, Xu J, Shu H, Xia J and Liu H et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475-481. doi: 10.1016/S2213-2600(20)30079-5.

Wang F, Wang H, Fan J, Zhang Y, Wang H and Zhao Q. Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia. Gastroenterology. 2020;159(1):367-370. doi: 10.1053/j.gastro.2020.03.055.