Visual Outcome and Topographic Parameters Stability after Corneal Ring Segment Surgery in Keratoconus

Topographic Parameters Stability after Corneal Ring Segment Surgery in Keratoconus

Authors

  • Saeed Zafar Khan Department of Ophthalmology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
  • Asad Aslam Khan College of Allied Health Sciences, King Edward Medical University, Lahore, Pakistan
  • Ammara Rasheed College of Allied Health Sciences, King Edward Medical University, Lahore, Pakistan
  • Rafia Saeed Department of Ophthalmology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
  • Amina Saeed Department of Ophthalmology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
  • Sajid Ali Department of Ophthalmology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
  • Abdul Majeed Malik Department of Ophthalmology, Fatima Memorial Hospital College of Medicine and Dentistry, Lahore, Pakistan
  • Waqar Ahmed Department of Ophthalmology, Northampton General Hospital, United Kingdom

DOI:

https://doi.org/10.54393/pjhs.v7i6.3908

Keywords:

Keratoconus, Ring Segments, Femtolaser, Kmax, Topography

Abstract

Keratoconus is a bilateral, non-inflammatory disease that leads to the bulging outward of a cone-shaped cornea affecting both genders. The major symptoms are blurring of vision, distortion of images, and difficulty in night driving. Objectives: To find the improvement in distance best corrected visual acuity (BCVA) and maximum keratometry (Kmax) from the baseline values up to three months following the implantation of ICRS. Methods: This study was employed as a retrospective consecutive cohort, which included all eligible keratoconus subjects visting Out Patient Department, Fatima Memorial Hospital. All twenty-five cases underwent a comprehensive clinical ocular examination followed by Pentacam corneal topography. Those willing for the Kerrara ring segment implant for visual rehabilitation were enrolled. All surgeries were performed by a single surgeon with Femtolaser technology. Results: A total of twenty-five subjects were implanted with Ferrara Rings. Regarding the visual outcome, a statistically significant improvement in uncorrected visual acuity (UCVA) was observed following implantation of the Ferrara cornea rings (p<0.001). Similarly, the K max values also demonstrated a decreasing trend from 52.88 ± 4.80 preoperatively to 50.42 ± 4.61 postoperatively (p<0.001). Hence, it was documented that a reduction in Kmax values indicates a significant flattening in corneal regularity and topographic stability after Ferrara segment implantation. Conclusions: The results of this observational study showed a significant improvement in visual acuity and a reduction in K max values due to the spacer effects of ICRS, resulting in an overall improvement in the quality of life of Keratoconus patients.

References

Moscovici BK, Rodrigues PF, Rodrigues RA, Rios LC, Simoncelli R, Freitas MM et al. Evaluation of Keratoconus Progression and Visual Improvement After Intrastromal Corneal Ring Segments Implantation: A Retrospective Study. European Journal of Ophthalmology. 2021 Nov; 31(6): 3483-9. doi: 10.1177/11206721211000646.

Navel V, Malecaze J, Pereira B, Baker JS, Malecaze F, Sapin V et al. Oxidative and Antioxidative Stress Markers in Keratoconus: A Systematic Review And Meta‐Analysis. Acta Ophthalmologica. 2021 Sep; 99(6): e777-94. doi: 10.1111/aos.14714.

D’Souza S, Nair AP, Sahu GR, Vaidya T, Shetty R, Khamar P et al. Keratoconus Patients Exhibit A Distinct Ocular Surface Immune Cell and Inflammatory Profile. Scientific Reports. 2021 Oct; 11(1): 20891. doi: 10.1038/s41598-021-99805-9.

Dal A, Canleblebici M, Kutluksaman B, Erdağ M. Effects and Safety of Combined Corneal Collagen Crosslinking and Intrastromal Corneal Ring Segment Treatment in Patients with Keratoconus: A Retrospective Study. BioMed Central Ophthalmology. 2024 Oct; 24(1): 473. doi: 10.1186/s12886-024-03745-7.

Costa JV, Monteiro T, Franqueira N, Faria-Correia F, Alfonso J, Vaz F. Five-Year Long-Term Outcomes of Intrastromal Corneal Ring Segment Implantation Using the Manual Technique for Keratoconus Management. Journal of Cataract and Refractive Surgery. 2021 Jun; 47(6): 713-21. doi: 10.1097/j.jcrs.0000000000000500.

Friedrich M, Auffarth GU, Soiberman U, Augustin VA, Khoramnia R, Son HS. Visual and Topographic Outcomes After Corneal Allogeneic Intrastromal Ring Segments for Keratoconus: A Systematic Review and Meta-Analysis. American Journal of Ophthalmology. 2025 Aug; 276: 81-91.

Elbassiouny KA, Hafez TA, Osman IA, Elmassry AA. Evaluation of Long-Term Outcomes of Simultaneous Corneal Collagen Cross-Linking and Femtosecond Laser-Assisted Intracorneal Ring Segment Implantation For Keratoconus. Journal of the Egyptian Ophthalmological Society. 2022 Apr; 115(2): 49-53. doi: 10.4103/ejos.ejos_65_21.

Coskunseven E, Kymionis GD, Tsiklis NS, Atun S, Arslan E, Jankov MR et al. One-Year Results of Intrastromal Corneal Ring Segment Implantation (Keraring) Using Femtosecond Laser in Patients with Keratoconus. American Journal of Ophthalmology. 2008 May; 145(5): 775-9. doi: 10.1016/j.ajo.2007.12.022.

Torquetti L and Ferrara P. The Ferrara Intrastromal Corneal Ring Segment Nomogram. In Keratoconus: A Comprehensive Guide to Diagnosis and Treatment. Cham: Springer International Publishing. 2022 Oct: 507-514. doi: 10.1007/978-3-030-85361-7_43.

Alió JL, Shabayek MH, Artola A. Intracorneal Ring Segments for Keratoconus Correction: Long-Term Follow-Up. Journal of Cataract and Refractive Surgery. 2006 Jun; 32(6): 978-85. doi: 10.1016/j.jcrs.2006.02.044.

Colin J and Malet FJ. Intacs for the Correction of Keratoconus: Two-Year Follow-Up. Journal of Cataract and Refractive Surgery. 2007 Jan; 33(1): 69-74. doi: 10.1016/j.jcrs.2006.08.057.

Ertan A and Kamburoğlu G. Intacs Implantation Using A Femtosecond Laser for Management of Keratoconus: Comparison of 306 Cases In Different Stages. Journal of Cataract and Refractive Surgery. 2008 Sep; 34(9): 1521-6. doi: 10.1016/j.jcrs.2008.05.028.

Sandes J, Ferrara P, Moscovici BK. Concentric Intrastromal Corneal Ring Implantation for Asymmetric Keratoconus: A Case Series. International Journal of Keratoconus and Ectatic Corneal Diseases. 2025 Apr; 11(1): 54-9. doi: 10.5005/jp-journals-10025-1210.

Vega-Estrada A, Del Barrio JA, Alio JL. Intracorneal Ring Segments and Keratoconus. In Controversies in the Management of Keratoconus. Cham: Springer International Publishing. 2018 Dec: 221-234. doi: 10.1007/978-3-319-98032-4_19.

Bautista-Llamas MJ, Sánchez-González MC, López-Izquierdo I, López-Muñoz A, Gargallo-Martínez B, De-Hita-Cantalejo C et al. Complications and Explantation Reasons in Intracorneal Ring Segments (ICRS) Implantation: A Systematic Review. Journal of Refractive Surgery. 2019 Nov; 35(11): 740-7. doi: 10.3928/1081597X-20191010-02.

D'Oria F, Abdelghany AA, Ledo N, Barraquer RI, Alio JL. Incidence and Reasons for Intrastromal Corneal Ring Segment Explantation. American Journal of Ophthalmology. 2021 Feb; 222: 351-8. doi: 10.1016/j.ajo.2020.09.041.

Larco P, Larco Jr P, Torres D, Piñero DP. Intracorneal Ring Segment Implantation for the Management of Keratoconus in Children. Vision. 2020 Dec; 5(1): 1. doi: 10.3390/vision5010001.

Prisant O, Pottier E, Guedj T, Xuan TH. Clinical Outcomes of an Asymmetric Model of Intrastromal Corneal Ring Segments for the Correction of Keratoconus. Cornea. 2020 Feb; 39(2): 155-60. doi: 10.1097/ICO.0000000000002160.

Izquierdo Jr L, Rodríguez AM, Sarquis RA, Altamirano D, Henriquez MA. Intracorneal Circular Ring Implant with Femtosecond Laser: Pocket Versus Tunnel. European Journal of Ophthalmology. 2022 Jan; 32(1): 176-82. doi: 10.1177/1120672121994729.

Monterosso C, Antonini M, Di Zazzo A, Gaudenzi D, Caretti L, Coassin M et al. Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty: A Safer Option in Keratoconus Surgery. European Journal of Ophthalmology. 2022 Jan; 32(1): 59-65. doi: 10.1177/11206721211059023.

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Published

2026-06-30
CITATION
DOI: 10.54393/pjhs.v7i6.3908
Published: 2026-06-30

How to Cite

Khan, S. Z., Khan, A. A., Rasheed, A., Saeed, R., Saeed, A., Ali, S., Malik, A. M., & Ahmed, W. (2026). Visual Outcome and Topographic Parameters Stability after Corneal Ring Segment Surgery in Keratoconus: Topographic Parameters Stability after Corneal Ring Segment Surgery in Keratoconus. Pakistan Journal of Health Sciences, 7(6), 75–80. https://doi.org/10.54393/pjhs.v7i6.3908

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