Frequency of Preeclampsia in Pregnant Women Presenting in A Tertiary Hospital

Frequency of Preeclampsia in Pregnant Women

Authors

  • Asifa Malhan Department of Obstetrics and Gynecology, Jinnah Postgraduate Medical College Hospital, Karachi, Pakistan
  • Mahruk Hyder Department of Obstetrics and Gynecology, Jinnah Postgraduate Medical College Hospital, Karachi, Pakistan
  • Shazia Baloch Department of Obstetrics and Gynecology, KMC Municipal Hospital, Jacobabad, Pakistan
  • Zahegul Department of Obstetrics and Gynecology, Civil Hospital, Karachi, Pakistan
  • Samiya Roshan Department of Obstetrics and Gynecology, Women Hospital, Larkana, Pakistan
  • Geeta Dembra Department of Obstetrics and Gynecology, Jinnah Postgraduate Medical College Hospital, Karachi, Pakistan
  • Maria Arshad Department of Obstetrics and Gynecology, CMH Multan, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i04.652

Keywords:

Preeclampsia, normotensive, pregnant women.

Abstract

Preeclampsia is pregnancy specific disorder that involves endothelial dysfunction and vasospam, so it needs prompt diagnosis and expert management as both mother and fetus are at risk. Objective: To determine the frequency of preeclampsia in pregnant women presenting in a tertiary hospital. Methods: This Cross-Sectional study was done in Department of Obstetrics and Gynecology, Unit-II ward-9, Jinnah Postgraduate Medical Centre, Karachi from 6th April 2018- 10th November 2018. We included 340  pregnant  females fulfilling the inclusion criteria. Informed consent was taken. The data were collected on prepared performa. Results: A total of 340 pregnant women were included in this study, mean age of patients was 28.3 ± 3.5 (16-30) years and mean gestational age in patients was 33.6 ± 5.2 in weeks. 49(14.4%) patients had pre-eclampsia while 291(85.6%) pregnant women were normotensive. Conclusions: Our results show patient with preeclampsia are at increased risk for morbidity and mortality of both new born and mother, so proper antenatal workup is required.

References

Mol BWJ, Roberts CT, Thangaratinam S, Magee LA, de Groot CJM, Hofmeyr GJ. Preeclampsia. Lancet. 2016 Mar; 387(10022): 999-1011. doi: 10.1016/S0140-6736(15)00070-7.

Ananth CV, Keyes KM, Wapner RJ. Preeclampsia rates in the United States, 1980- 2010: age-period-cohort analysis. BMJ 2013 Nov; 347: f6564. doi: 10.1136/bmj.f6564.

Gestational hypertension and preeclampsia: ACOG Practice Bulletin, Number 222. Obstetric Gynecology 2020 Jun; 135(6): e237-e260. doi: 10.1097/AOG.0000000000003891.

Dzakpasu S, Deb-Rinker P, Arbour L, Darling EK, Kramer MS, Liu S, et al. Severe maternal morbidity in Canada: temporal trends and regional variations, 2003-16. Journal of Obstetrics and Gynaecology Canada. 2019 Nov; 41(11): 1589-98.

Roberts JM and Hubel CA. The two-stage model of preeclampsia: variations on the theme. Placenta 2009 Mar; 30(Suppl A): S32-7. doi: 10.1016/j.placenta.2008.11.009

Lisonkova S and Joseph KS. Incidence of preeclampsia: risk factors and outcomes associated with early-versus late-onset disease. American journal of obstetrics and gynecology. 2013 Dec; 209(6): 544-e1. doi: 10.1016/j.ajog.2013.08.019.

Wilkerson RG and Ogunbodede AC. Hypertensive disorders of pregnancy. Emergency Medicine Clinics. 2019 May; 37(2): 301-16. doi: 10.1016/j.emc.2019.01.008

Sutton AL, Harper LM, Tita AT. Hypertensive disorders in pregnancy. Obstetrics and Gynecology Clinics. 2018 Jun; 45(2): 333-47. doi: 10.1016/j.ogc.2018.01.012

Fitzpatrick KE, Hinshaw K, Kurinczuk JJ, Knight M. Risk factors, management, and outcomes of hemolysis, elevated liver enzymes, and low platelets syndrome and elevated liver enzymes, low platelets syndrome. Obstetrics and Gynecology. 2014 Mar; 123(3): 618-27. doi: 10.1097/AOG.0000000000000140.

Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstetric Gynecology. 2004 May; 103(5 Pt 1): 981-91. doi: 10.1097/01.AOG.0000126245.35811.2a

Lisonkova S, Razaz N, Sabr Y, Muraca GM, Boutin A, Mayer C, et al. Maternal risk factors and adverse birth outcomes associated with HELLP syndrome: a population‐based study. BJOG: An International Journal of Obstetrics & Gynaecology. 2020 Sep; 127(10): 1189-98. doi: 10.1111/1471-0528.16225.

Guerrier G, Oluyide B, Keramarou M, Grais RF. Factors associated with severe preeclampsia and eclampsia in Jahun, Nigeria. International Journal of Women's Health. 2013 Aug: 509-13. doi: 10.2147/IJWH.S47056.

Kaaja R, Kinnunen T, Luoto R. Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland. European Heart Journal. 2005 Jan; 26(1): 44-50. doi: 10.1093/eurheartj/ehi015.

Agrawal, S. Prevalence and risk factors for symptoms suggestive of pre-eclampsia in Indian women. Journal of Women’s Health Issues Care. 2014 Oct; 3(6): 2–9.

Akter K and Khanum H. Prevalance of pre-eclampsia and factors responsible among third trimester pregnant women in hospital of Dhaka. Biomedical Journal of Scientific & Technical Research. 2021; 33(4): 26089-97.

Belay AS and Wudad T. Prevalence and associated factors of pre-eclampsia among pregnant women attending anti-natal care at Mettu Karl referal hospital, Ethiopia: cross-sectional study. Clinical Hypertension. 2019 Dec; 25(1): 1-8. doi: 10.1186/s40885-019-0120-1.

Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel JP, et al. Pre‐eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG: An International Journal of Obstetrics & Gynaecology. 2014 Mar; 121: 14-24. doi: 10.1111/1471-0528.12629.

Lisonkova S and Joseph KS. Incidence of preeclampsia: risk factors and outcomes associated with early-versus late-onset disease. American Journal of Obstetrics and Gynecology. 2013 Dec; 209(6): 544-e1. doi: 10.1016/j.ajog.

Weissgerber TL and Mudd LM. Preeclampsia and diabetes. Current Diabetes Reports. 2015 Mar; 15:1-0. doi: 10.1007/s11892-015-0579-4.

Moussa HN, Arian SE, Sibai BM. Management of hypertensive disorders in pregnancy. Women’s Health. 2014 Jul; 10(4): 385-404. doi: 10.2217/whe.14.32

Downloads

Published

2023-04-30
CITATION
DOI: 10.54393/pjhs.v4i04.652
Published: 2023-04-30

How to Cite

Malhan, A., Hyder, M. ., Baloch , S. ., Zahegul, Roshan, S., Dembra, G., & Arshad, M. (2023). Frequency of Preeclampsia in Pregnant Women Presenting in A Tertiary Hospital: Frequency of Preeclampsia in Pregnant Women. Pakistan Journal of Health Sciences, 4(04), 30–33. https://doi.org/10.54393/pjhs.v4i04.652

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)